|
🐬
|
mTOR: from growth signal integration to cancer, diabetes and ageing
R. Zoncu,
A. Efeyan,
D. Sabatini
|
11 |
2010 |
11
🐬
|
|
🐬
|
mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase
R. Zoncu,
L. Bar-Peled,
A. Efeyan,
Shuyu Wang,
Y. Sancak,
D. Sabatini
|
10 |
2011 |
10
🐬
|
|
🐜
|
Tumour biology: Senescence in premalignant tumours
12 auth.
M. Collado,
J. Gil,
A. Efeyan,
C. Guerra,
A. J. Schuhmacher,
M. Barradas,
...
A. Benguría,
Á. Zaballos,
J. Flores,
M. Barbacid,
D. Beach,
M. Serrano
|
10 |
2005 |
10
🐜
|
|
🦁
|
Nutrient-sensing mechanisms and pathways
A. Efeyan,
William C. Comb,
D. Sabatini
|
9 |
2015 |
9
🦁
|
|
🦁
|
mTOR and cancer: many loops in one pathway.
A. Efeyan,
D. Sabatini
|
8 |
2009 |
8
🦁
|
|
🦁
|
Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival
9 auth.
A. Efeyan,
R. Zoncu,
Steven Chang,
I. Gumper,
Harriet Snitkin,
Rachel L. Wolfson,
...
O. Kirak,
D. Sabatini,
D. Sabatini
|
8 |
2012 |
8
🦁
|
|
🦁
|
Amino acids and mTORC1: from lysosomes to disease.
A. Efeyan,
R. Zoncu,
D. Sabatini
|
8 |
2012 |
8
🦁
|
|
🦁
|
p53: Guardian of the Genome and Policeman of the Oncogenes
A. Efeyan,
M. Serrano
|
8 |
2007 |
8
🦁
|
|
🐜
|
Pten positively regulates brown adipose function, energy expenditure, and longevity.
15 auth.
Ana Ortega-Molina,
A. Efeyan,
Elena Lopez-Guadamillas,
Maribel Muñoz-Martín,
G. Gómez-López,
M. Cañamero,
F. Mulero,
J. Pastor,
Sonia Martínez,
Eduardo Romanos,
...
M. Mar González-Barroso,
E. Rial,
Á. Valverde,
J. Bischoff,
M. Serrano
|
8 |
2012 |
8
🐜
|
|
🐜
|
Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
9 auth.
Jonatan Ersching,
A. Efeyan,
L. Mesin,
Johanne T. Jacobsen,
G. Pasqual,
Brian C. Grabiner,
...
D. Dominguez-Sola,
D. Sabatini,
G. Victora
|
7 |
2017 |
7
🐜
|
|
🐢
|
The mTOR–Autophagy Axis and the Control of Metabolism
Nerea Deleyto-Seldas,
A. Efeyan
|
7 |
2021 |
7
🐢
|
|
🐜
|
Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma
35 auth.
J. Okosun,
Rachel L. Wolfson,
Jun Wang,
S. Araf,
Lucy Wilkins,
Brian M. Castellano,
L. Escudero-Ibarz,
Ahad Al Seraihi,
J. Richter,
S. Bernhart,
A. Efeyan,
S. Iqbal,
J. Matthews,
A. Clear,
J. A. Guerra-Assunção,
...
C. Bödör,
H. Quentmeier,
Christopher T. Mansbridge,
Peter W M Johnson,
A. Davies,
J. Strefford,
G. Packham,
S. Barrans,
A. Jack,
M. Du,
M. Calaminici,
T. A. Lister,
R. Auer,
S. Montoto,
J. Gribben,
R. Siebert,
C. Chelala,
R. Zoncu,
D. Sabatini,
J. Fitzgibbon
|
7 |
2015 |
7
🐜
|
|
🐜
|
mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer
64 auth.
Amaia Zabala-Letona,
Amaia Arruabarrena-Aristorena,
Natalia Martín-Martín,
Sonia Fernández-Ruiz,
J. Sutherland,
Michelle F. Clasquin,
Julen Tomás-Cortázar,
J. Jiménez,
Inés M. Torres,
Phong Quang,
P. Ximénez-Embún,
R. Bago,
Aitziber Ugalde-Olano,
Ana Loizaga-Iriarte,
Isabel Lacasa-Viscasillas,
...
M. Unda,
V. Torrano,
D. Cabrera,
S. van Liempd,
Y. Cendón,
E. Castro,
Stuart Murray,
Ajinkya Revandkar,
A. Alimonti,
Yinan Zhang,
Amelia Barnett,
G. Lein,
David A. Pirman,
A. R. Cortázar,
Leire Arreal,
L. Prudkin,
I. Astobiza,
Lorea Valcarcel-Jimenez,
P. Zuniga-Garcia,
Itziar Fernández-Domínguez,
M. Piva,
A. Caro-Maldonado,
Pilar Sánchez-Mosquera,
M. Castillo-Martin,
V. Serra,
N. Beraza,
A. Gentilella,
G. Thomas,
M. Azkargorta,
F. Elortza,
R. Farràs,
D. Olmos,
A. Efeyan,
J. Anguita,
J. Muñoz,
J. Falcón-Perez,
R. Barrio,
T. Macarulla,
J. Mato,
M. Martínez‐Chantar,
C. Cordon-Cardo,
A. Aransay,
K. Marks,
J. Baselga,
J. Tabernero,
P. Nuciforo,
B. Manning,
Katya Marjon,
A. Carracedo
|
7 |
2017 |
7
🐜
|
