|
π
|
STING is a direct innate immune sensor of cyclic-di-GMP
8 auth.
Dara L Burdette,
K. Monroe,
Katia Sotelo-Troha,
J. Iwig,
B. Eckert,
M. Hyodo,
...
Y. Hayakawa,
R. Vance
|
10 |
2011 |
10
π
|
|
π
|
Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
11 auth.
G. Doitsh,
N. Galloway,
X. Geng,
Zhiyuan Yang,
K. Monroe,
O. Zepeda,
...
P. Hunt,
H. Hatano,
S. Sowinski,
Isa MuΓ±oz-Arias,
W. Greene
|
10 |
2013 |
10
π
|
|
π
|
The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING.
9 auth.
Elie J. Diner,
Dara L Burdette,
Stephen C. Wilson,
K. Monroe,
C. A. Kellenberger,
M. Hyodo,
...
Y. Hayakawa,
M. C. Hammond,
R. Vance
|
9 |
2013 |
9
π
|
|
π
|
The N-Ethyl-N-Nitrosourea-Induced Goldenticket Mouse Mutant Reveals an Essential Function of Sting in the In Vivo Interferon Response to Listeria monocytogenes and Cyclic Dinucleotides
11 auth.
J. Sauer,
Katia Sotelo-Troha,
Jakob von Moltke,
K. Monroe,
Chris S. Rae,
Sky W. Brubaker,
...
M. Hyodo,
Y. Hayakawa,
J. Woodward,
D. Portnoy,
R. Vance
|
9 |
2010 |
9
π
|
|
π¦
|
IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV
7 auth.
K. Monroe,
Zhiyuan Yang,
Jeffrey R. Johnson,
X. Geng,
G. Doitsh,
N. Krogan,
...
W. Greene
|
8 |
2014 |
8
π¦
|
|
π
|
TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge
30 auth.
Alicia A. Nugent,
Karin Lin,
B. Lengerich,
Steve Lianoglou,
Laralynne Przybyla,
Sonnet S. Davis,
Ceyda Llapashtica,
Junhua Wang,
Do Jin Kim,
D. Xia,
A. Lucas,
S. Baskaran,
P. C. Haddick,
Melina Lenser,
Timothy Earr,
...
Ju Shi,
J. Dugas,
Benjamin J. Andreone,
Todd Logan,
Hilda Solanoy,
Hang Chen,
Ankita Srivastava,
S. Poda,
P. Sanchez,
R. Watts,
T. Sandmann,
G. Astarita,
Joseph W. Lewcock,
K. Monroe,
G. D. Paolo
|
8 |
2019 |
8
π
|
|
π
|
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-ΞΊB signaling pathways.
15 auth.
I. C. Allen,
C. Moore,
Monika Schneider,
Y. Lei,
B. Davis,
Margaret A. Scull,
Denis Gris,
Kelly E. Roney,
A. Zimmermann,
J. Bowzard,
...
P. Ranjan,
K. Monroe,
R. Pickles,
S. Sambhara,
J. Ting
|
8 |
2011 |
8
π
|
|
π
|
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
13 auth.
S. McWhirter,
Roman Barbalat,
K. Monroe,
Mary F. Fontana,
M. Hyodo,
N. Joncker,
K. Ishii,
S. Akira,
M. Colonna,
Zhijian J. Chen,
...
K. Fitzgerald,
Y. Hayakawa,
R. Vance
|
8 |
2009 |
8
π
|
|
π¦
|
Identification of Host Cytosolic Sensors and Bacterial Factors Regulating the Type I Interferon Response to Legionella pneumophila
K. Monroe,
S. McWhirter,
R. Vance
|
7 |
2009 |
7
π¦
|
|
π
|
Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region
28 auth.
K. Schlepckow,
K. Monroe,
G. Kleinberger,
Ludovico Cantuti-Castelvetri,
S. Parhizkar,
D. Xia,
M. Willem,
G. Werner,
Nadine Pettkus,
B. Brunner,
Alice SΓΌlzen,
Brigitte Nuscher,
H. Hampel,
X. Xiang,
R. Feederle,
...
S. Tahirovic,
Joshua I. Park,
Rachel Prorok,
Cathal S. Mahon,
Chun-Chi Liang,
Ju Shi,
Do Jin Kim,
H. SabelstrΓΆm,
F. Huang,
G. Di Paolo,
M. Simons,
Joseph W. Lewcock,
C. Haass
|
7 |
2020 |
7
π
|
|
π
|
Alzheimerβs-associated PLCΞ³2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia
14 auth.
Benjamin J. Andreone,
Laralynne Przybyla,
Ceyda Llapashtica,
A. Rana,
Sonnet S. Davis,
Bettina van Lengerich,
Karin Lin,
Ju Shi,
Y. Mei,
G. Astarita,
...
G. Di Paolo,
T. Sandmann,
K. Monroe,
Joseph W. Lewcock
|
7 |
2020 |
7
π
|
|
π
|
Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells.
7 auth.
N. Galloway,
G. Doitsh,
K. Monroe,
Zhiyuan Yang,
Isa MuΓ±oz-Arias,
D. N. Levy,
...
W. Greene
|
7 |
2015 |
7
π
|
