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🐜
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A Phase Ib Trial of Personalized Neoantigen Therapy Plus Anti-PD-1 in Patients with Advanced Melanoma, Non-small Cell Lung Cancer, or Bladder Cancer
39 auth.
P. Ott,
S. Hu-Lieskovan,
B. Chmielowski,
R. Govindan,
A. Naing,
N. Bhardwaj,
K. Margolin,
M. Awad,
M. Hellmann,
Jessica J. Lin,
T. Friedlander,
M. Bushway,
Kristen N Balogh,
Tracey E. Sciuto,
Victoria L. Kohler,
...
S. Turnbull,
Rana H. Besada,
Riley R. Curran,
Benjamin Trapp,
J. Scherer,
A. Poran,
D. Harjanto,
D. Barthelme,
Ying S. Ting,
Jesse Z. Dong,
Yvonne Ware,
Yuting Huang,
Zhengping Huang,
Amy Wanamaker,
Lisa D. Cleary,
M. A. Moles,
K. Manson,
J. Greshock,
Z. Khondker,
E. Fritsch,
Michael S. Rooney,
M. DeMario,
R. Gaynor,
L. Srinivasan
|
8 |
2020 |
8
🐜
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|
🐜
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A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors
17 auth.
J. Rodón,
H. Tawbi,
Anne L. Thomas,
R. Stoller,
C. Turtschi,
J. Baselga,
J. Sarantopoulos,
D. Mahalingam,
Y. Shou,
M. A. Moles,
...
Lin Yang,
C. Granvil,
E. Hurh,
Kristine L. Rose,
D. Amakye,
R. Dummer,
A. Mita
|
7 |
2014 |
7
🐜
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|
🐜
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Personalized neoantigen vaccine NEO-PV-01 with chemotherapy and anti-PD-1 as first-line treatment for non-squamous non-small cell lung cancer.
24 auth.
M. Awad,
R. Govindan,
Kristen N Balogh,
D. Spigel,
E. Garon,
M. Bushway,
A. Poran,
J. Sheen,
Victoria L. Kohler,
Ekaterina Esaulova,
...
John Srouji,
Suchitra Ramesh,
Rohit Vyasamneni,
Binisha Karki,
Tracey E. Sciuto,
H. Sethi,
Jesse Z. Dong,
M. A. Moles,
K. Manson,
Michael S. Rooney,
Z. Khondker,
M. DeMario,
Richard B. Gaynor,
L. Srinivasan
|
6 |
2022 |
6
🐜
|
|
🐜
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A personal neoantigen vaccine, NEO-PV-01, with anti-PD1 induces broad de novo anti-tumor immunity in patients with metastatic melanoma, NSCLC, and bladder cancer.
14 auth.
P. Ott,
R. Govindan,
A. Naing,
Terence W Friedlander,
K. Margolin,
Jessica J. Lin,
N. Bhardwaj,
M. Hellman,
L. Srinivasan,
J. Greshock,
...
M. A. Moles,
Richard B. Gaynor,
Matthew J. Goldstein,
S. Hu-Lieskovan
|
4 |
2018 |
4
🐜
|
|
🐜
|
Abstract 942: The personalized vaccine, NEO-PV-01 with anti-PD1, induces neoantigen-specific de novo immune responses in patients with advanced metastatic melanoma: Association with clinical outcomes
25 auth.
S. Hu-Lieskovan,
P. Ott,
A. Naing,
Rana H. Besada,
Samantha J. Gates,
Victoria R. Kohler,
Riley R. Curran,
M. Bushway,
J. Scherer,
Kristen N Balogh,
Tracey E. Sciuto,
Ying S. Ting,
Michael S. Rooney,
D. Harjanto,
Zhengping Huang,
...
Yuting Huang,
Yvonne Ware,
A. Lamb,
Lisa D. Cleary,
M. A. Moles,
R. Gaynor,
M. Goldstein,
L. Brail,
J. Greshock,
L. Srinivasan
|
3 |
2019 |
3
🐜
|
|
🐜
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Abstract CT125: A personal neoantigen vaccine, NEO-PV-01, with anti-PD1 induces broadde novoanti-tumor immunity in patients with metastatic melanoma, NSCLC, and bladder cancer
14 auth.
P. Ott,
R. Govindan,
A. Naing,
T. Friedlander,
K. Margolin,
Jessica J. Lin,
N. Bhardwaj,
M. Hellmann,
L. Srinivasan,
J. Greshock,
...
M. A. Moles,
R. Gaynor,
M. Goldstein,
S. Hu-Lieskovan
|
2 |
2018 |
2
🐜
|
|
🐜
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An open-label, phase 1b study of NEO-PV-01 with pembrolizumab plus chemotherapy in patients with advanced or metastatic nonsquamous non-small cell lung cancer.
7 auth.
R. Govindan,
M. Awad,
Lisa D. Cleary,
M. A. Moles,
R. Gaynor,
M. Goldstein,
...
D. Spigel
|
2 |
2018 |
2
🐜
|
|
🐜
|
Abstract 73: A personal neoantigen vaccine NEO-PV-01 in combination with chemotherapy and pembrolizumab induces broad de novo immune responses in first-line non-squamous NSCLC: Associations with clinical outcomes
20 auth.
M. Awad,
R. Govindan,
D. Spigel,
E. Garon,
Victoria L. Kohler,
Rohit Vyasamneni,
Suchitra Ramesh,
Tracey E. Sciuto,
M. A. Moles,
Jennifer Tepper,
...
Amy Wanamaker,
Zakaria S. Khondkar,
John Srouji,
Jesse Z. Dong,
Kristen N Balogh,
A. Poran,
M. Bushway,
M. DeMario,
Richard B. Gaynor,
L. Srinivasan
|
1 |
2021 |
1
🐜
|
|
🐜
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1207TiPAn open-label, Phase IB study of NEO-PV-01 + Adjuvant with Nivolumab in Patients with Melanoma, Non-Small Cell Lung Carcinoma, or Transitional Cell Carcinoma of the Bladder
8 auth.
P. Ott,
A. Naing,
G. Ramaswamy,
K. Margolin,
M. A. Moles,
R. Gaynor,
...
M. Goldstein,
S. Hu-Lieskovan
|
0 |
2017 |
0
🐜
|
