|
π
|
RUNX1 Is a Key Target in t(4;11) Leukemias that Contributes to Gene Activation through an AF4-MLL Complex Interaction
13 auth.
A. Wilkinson,
E. Ballabio,
H. Geng,
H. Geng,
P. North,
M. Tapia,
J. Kerry,
Debabrata Biswas,
R. Roeder,
C. Allis,
...
A. Melnick,
M. D. Bruijn,
T. Milne
|
7 |
2013 |
7
π
|
|
π
|
MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199
36 auth.
J. Benito,
Laura J. Godfrey,
K. Kojima,
L. Hogdal,
M. Wunderlich,
H. Geng,
I. Marzo,
Karine G. Harutyunyan,
L. Golfman,
P. North,
J. Kerry,
E. Ballabio,
T. Chonghaile,
Γscar Gonzalo,
Y. Qiu,
...
I. Jeremias,
Lakiesha Debose,
Eric O'Brien,
Helen Ma,
P. Zhou,
R. Jacamo,
E. Park,
K. Coombes,
Nianxiang Zhang,
D. Thomas,
S. O'brien,
H. Kantarjian,
J. Leverson,
S. Kornblau,
M. Andreeff,
M. MΓΌschen,
P. Zweidler-McKay,
J. Mulloy,
A. Letai,
T. Milne,
M. Konopleva
|
7 |
2015 |
7
π
|
|
π
|
The chromatin remodelling factor ATRX suppresses Rβloops in transcribed telomeric repeats
16 auth.
D. Nguyen,
H. P. Voon,
Barbara Xella,
Caroline Scott,
David Clynes,
C. Babbs,
H. Ayyub,
J. Kerry,
J. Sharpe,
J. Sloane-Stanley,
...
Sue Butler,
C. Fisher,
Nicki Gray,
T. Jenuwein,
D. Higgs,
R. Gibbons
|
6 |
2017 |
6
π
|
|
π
|
Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia.
17 auth.
Shan Lin,
R. Luo,
A. Ptasinska,
J. Kerry,
Salam A. Assi,
M. Wunderlich,
T. Imamura,
J. Kaberlein,
Ahmad Rayes,
M. Althoff,
...
J. Anastasi,
M. OβBrien,
A. R. Meetei,
T. Milne,
C. Bonifer,
J. Mulloy,
M. Thirman
|
6 |
2016 |
6
π
|
|
π
|
Editing an Ξ±-globin enhancer in primary human hematopoietic stem cells as a treatment for Ξ²-thalassemia
22 auth.
S. Mettananda,
C. Fisher,
Deborah Hay,
M. Badat,
L. Quek,
Kevin D. Clark,
P. Hublitz,
D. Downes,
J. Kerry,
M. Gosden,
...
Jelena M. Telenius,
J. Sloane-Stanley,
P. Faustino,
A. Coelho,
Jessica B. Doondeea,
B. Usukhbayar,
P. Sopp,
J. Sharpe,
J. Hughes,
P. Vyas,
R. Gibbons,
D. Higgs
|
6 |
2017 |
6
π
|
|
π
|
BET inhibition disrupts transcription but retains enhancer-promoter contact
12 auth.
N. Crump,
E. Ballabio,
Laura J. Godfrey,
Ross Thorne,
E. Repapi,
J. Kerry,
...
M. Tapia,
Peng Hua,
Christoffer Lagerholm,
P. Filippakopoulos,
J. Davies,
T. Milne
|
6 |
2019 |
6
π
|
|
π
|
Dynamics of the 4D genome during in vivo lineage specification and differentiation
17 auth.
A. M. Oudelaar,
Robert A. Beagrie,
M. Gosden,
S. D. Ornellas,
E. Georgiades,
J. Kerry,
Daniel Hidalgo,
J. Carrelha,
Arun Shivalingam,
A. El-Sagheer,
...
A. El-Sagheer,
Jelena M. Telenius,
T. Brown,
V. Buckle,
M. Socolovsky,
D. Higgs,
Jim R. Hughes
|
6 |
2020 |
6
π
|
|
π¦
|
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia
16 auth.
J. Kerry,
Laura J. Godfrey,
E. Repapi,
M. Tapia,
Neil P. Blackledge,
Helen Ma,
E. Ballabio,
Sorcha OβByrne,
F. Ponthan,
O. Heidenreich,
...
A. Roy,
I. Roberts,
M. Konopleva,
R. Klose,
H. Geng,
T. Milne
|
6 |
2017 |
6
π¦
|
|
π
|
High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale
19 auth.
D. Downes,
Robert A. Beagrie,
M. Gosden,
Jelena M. Telenius,
Stephanie J. Carpenter,
L. Nussbaum,
Sara de Ornellas,
M. Sergeant,
Chris Eijsbouts,
R. Schwessinger,
...
J. Kerry,
N. Roberts,
Arun Shivalingam,
A. El-Sagheer,
A. M. Oudelaar,
T. Brown,
V. Buckle,
J. Davies,
J. Hughes
|
4 |
2021 |
4
π
|
