|
π
|
Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells
31 auth.
E. Deenick,
D. Avery,
A. Chan,
L. Berglund,
Megan L. Ives,
Leen Moens,
J. Stoddard,
J. Bustamante,
S. Boisson-Dupuis,
M. Tsumura,
Masao Kobayashi,
P. Arkwright,
D. Averbuch,
D. Engelhard,
J. Roesler,
...
J. Peake,
M. Wong,
S. Adelstein,
S. Choo,
Joanne M. Smart,
M. French,
D. Fulcher,
M. Cook,
C. Picard,
A. Durandy,
C. Klein,
S. Holland,
G. Uzel,
J. Casanova,
Cindy S. Ma,
S. Tangye
|
7 |
2013 |
7
π
|
|
π
|
IL-21 is the primary common Ξ³ chain-binding cytokine required for human B-cell differentiation in vivo.
24 auth.
M. Recher,
L. Berglund,
D. Avery,
M. Cowan,
A. Gennery,
Joanne M. Smart,
J. Peake,
M. Wong,
S. Pai,
S. Baxi,
...
J. Walter,
U. Palendira,
Gillian A Tangye,
Michael Rice,
S. Brothers,
W. Al-Herz,
H. Oettgen,
H. Eibel,
J. Puck,
F. Cattaneo,
J. Ziegler,
S. Giliani,
S. Tangye,
L. Notarangelo
|
7 |
2011 |
7
π
|
|
π¦
|
IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts.
24 auth.
L. Berglund,
D. Avery,
Cindy S. Ma,
Leen Moens,
E. Deenick,
J. Bustamante,
S. Boisson-Dupuis,
M. Wong,
S. Adelstein,
P. Arkwright,
...
R. Bacchetta,
L. Bezrodnik,
H. Dadi,
C. Roifman,
D. Fulcher,
J. Ziegler,
Joanne M. Smart,
Masao Kobayashi,
C. Picard,
A. Durandy,
M. Cook,
J. Casanova,
G. Uzel,
S. Tangye
|
6 |
2013 |
6
π¦
|
|
π
|
Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity
18 auth.
E. Edwards,
Julia Bier,
T. Cole,
M. Wong,
P. Hsu,
L. Berglund,
K. Boztug,
A. Lau,
E. Gostick,
D. Price,
...
Michael OβSullivan,
I. Meyts,
S. Choo,
Paul E A Gray,
S. Holland,
E. Deenick,
G. Uzel,
S. Tangye
|
6 |
2019 |
6
π
|
|
π
|
Germline-activating mutations in PIK3CD compromise B cell development and function
34 auth.
D. Avery,
A. Kane,
T. Nguyen,
A. Lau,
A. Nguyen,
Helen Lenthall,
Kathryn J. Payne,
Wei Shi,
Henry Brigden,
E. French,
Julia Bier,
Jana R. Hermes,
D. Zahra,
W. Sewell,
Danyal Butt,
...
Michael Elliott,
K. Boztug,
I. Meyts,
S. Choo,
P. Hsu,
M. Wong,
L. Berglund,
P. Gray,
Michael OβSullivan,
T. Cole,
S. Holland,
Cindy S. Ma,
C. Burkhart,
L. Corcoran,
T. Phan,
R. Brink,
G. Uzel,
E. Deenick,
S. Tangye
|
6 |
2018 |
6
π
|
|
π
|
Decrease in phenotypic regulatory T cells in subsets of patients with common variable immunodeficiency
7 auth.
J. Horn,
A. Manguiat,
L. Berglund,
V. Knerr,
F. Tahami,
B. Grimbacher,
...
D. Fulcher
|
6 |
2009 |
6
π
|
|
π
|
Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4+ T cells.
28 auth.
Julia Bier,
Geetha Rao,
Kathryn J. Payne,
Henry Brigden,
E. French,
Simon J. Pelham,
A. Lau,
Helen Lenthall,
E. Edwards,
Joanne M. Smart,
T. Cole,
S. Choo,
A. Joshi,
R. Abraham,
Michael OβSullivan,
...
K. Boztug,
I. Meyts,
P. Gray,
L. Berglund,
P. Hsu,
M. Wong,
S. Holland,
L. Notarangelo,
G. Uzel,
Cindy S. Ma,
R. Brink,
S. Tangye,
E. Deenick
|
5 |
2019 |
5
π
|
|
π¦
|
Bβcell maturation defects in common variable immunodeficiency and association with clinical features
L. Berglund,
Sue W. J. Wong,
D. Fulcher
|
5 |
2008 |
5
π¦
|
|
π
|
Activated PI3KΞ΄ breaches multiple B cell tolerance checkpoints and causes autoantibody production
25 auth.
A. Lau,
D. Avery,
Katherine J. L. Jackson,
Helen Lenthall,
S. Volpi,
Henry Brigden,
A. Russell,
Julia Bier,
J. Reed,
Joanne M. Smart,
T. Cole,
S. Choo,
P. Gray,
L. Berglund,
P. Hsu,
...
M. Wong,
Michael OβSullivan,
K. Boztug,
I. Meyts,
G. Uzel,
L. Notarangelo,
R. Brink,
C. Goodnow,
S. Tangye,
E. Deenick
|
5 |
2019 |
5
π
|
