|
π¦
|
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
18 auth.
E. Greggio,
S. Jain,
A. Kingsbury,
R. Bandopadhyay,
P. Lewis,
Alice Kaganovich,
M. Brug,
A. Beilina,
J. Blackinton,
K. J. Thomas,
...
Rili Ahmad,
David W. Miller,
S. Kesavapany,
A. Singleton,
A. Lees,
R. Harvey,
K. Harvey,
M. Cookson
|
9 |
2006 |
9
π¦
|
|
π
|
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
21 auth.
A. Beilina,
I. Rudenko,
Alice Kaganovich,
L. Civiero,
Hien N. Chau,
Suneil K. Kalia,
Lorraine V. Kalia,
Evy Lobbestael,
Ruth Chia,
K. Ndukwe,
...
Jinhui Ding,
M. Nalls,
M. Olszewski,
David N. Hauser,
R. Kumaran,
A. Lozano,
V. Baekelandt,
L. Greene,
J. Taymans,
E. Greggio,
M. Cookson
|
8 |
2014 |
8
π
|
|
π¦
|
The Parkinson Disease-associated Leucine-rich Repeat Kinase 2 (LRRK2) Is a Dimer That Undergoes Intramolecular Autophosphorylation*
13 auth.
E. Greggio,
Ibardo A. Zambrano,
Alice Kaganovich,
A. Beilina,
J. Taymans,
V. DaniΓ«ls,
P. Lewis,
S. Jain,
Jinhui Ding,
Ali Syed,
...
K. J. Thomas,
V. Baekelandt,
M. Cookson
|
8 |
2008 |
8
π¦
|
|
π¬
|
The R1441C mutation of LRRK2 disrupts GTP hydrolysis.
P. Lewis,
E. Greggio,
A. Beilina,
S. Jain,
Acacia K Baker,
M. Cookson
|
8 |
2007 |
8
π¬
|
|
π¦
|
Leucine-rich repeat kinase 2 mutations and Parkinsonβs disease: three questions
E. Greggio,
M. Cookson
|
8 |
2009 |
8
π¦
|
|
π
|
Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1*
8 auth.
J. Blackinton,
M. Lakshminarasimhan,
K. J. Thomas,
Rili Ahmad,
E. Greggio,
A. Raza,
...
M. Cookson,
M. Wilson
|
7 |
2009 |
7
π
|
|
π¬
|
Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase
Junpeng Deng,
P. Lewis,
E. Greggio,
Eli Sluch,
A. Beilina,
M. Cookson
|
7 |
2008 |
7
π¬
|
|
π
|
The Chaperone Activity of Heat Shock Protein 90 Is Critical for Maintaining the Stability of Leucine-Rich Repeat Kinase 2
16 auth.
Lizheng Wang,
Chengsong Xie,
E. Greggio,
L. Parisiadou,
Hoon Shim,
Lixin Sun,
J. Chandran,
Xian Lin,
Chen Lai,
Wan-Jou Yang,
...
D. Moore,
T. Dawson,
V. Dawson,
G. Chiosis,
M. Cookson,
H. Cai
|
7 |
2008 |
7
π
|
|
π’
|
LRRK2 and neuroinflammation: partners in crime in Parkinsonβs disease?
Isabella Russo,
L. Bubacco,
E. Greggio
|
7 |
2014 |
7
π’
|
|
π¦
|
The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites.
12 auth.
E. Greggio,
J. Taymans,
Eugene Y. Zhen,
J. Ryder,
R. Vancraenenbroeck,
A. Beilina,
...
Peng Sun,
Junpeng Deng,
H. Jaffe,
V. Baekelandt,
Kalpana M. Merchant,
M. Cookson
|
7 |
2009 |
7
π¦
|
|
π
|
GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2.
7 auth.
Alice Biosa,
A. TranΔΓkova,
L. Civiero,
Liliane Glauser,
L. Bubacco,
E. Greggio,
...
D. Moore
|
7 |
2013 |
7
π
|
