|
🐜
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Mutations in the DNA methyltransferase gene, DNMT3A, cause an overgrowth syndrome with intellectual disability
23 auth.
K. Tatton-Brown,
S. Seal,
Elise Ruark,
J. Harmer,
Emma Ramsay,
Silvana del Vecchio Duarte,
A. Zachariou,
S. Hanks,
Eleanor M. O’Brien,
L. Aksglaede,
...
D. Baralle,
T. Dabir,
B. Gener,
D. Goudie,
T. Homfray,
Ajith Kumar,
D. Pilz,
A. Selicorni,
I. Temple,
Lionel Van Maldergem,
Naomi Yachelevich,
Robert van Montfort,
N. Rahman
|
8 |
2014 |
8
🐜
|
|
🐜
|
X-ray crystallographic and EPR spectroscopic analysis of HydG, a maturase in [FeFe]-hydrogenase H-cluster assembly
10 auth.
P. Dinis,
D. Suess,
Stephen J. Fox,
J. Harmer,
Rebecca C. Driesener,
L. De La Paz,
...
James R. Swartz,
J. Essex,
R. David Britt,
Peter L. Roach
|
6 |
2015 |
6
🐜
|
|
🦁
|
Structures of lipoyl synthase reveal a compact active site for controlling sequential sulfur insertion reactions.
10 auth.
J. Harmer,
Martyn J Hiscox,
P. Dinis,
S. Fox,
Andreas Iliopoulos,
J. E. Hussey,
...
J. Sandy,
Florian T Van Beek,
J. Essex,
P. Roach
|
5 |
2014 |
5
🦁
|
|
🐜
|
Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives.
24 auth.
D. Tisi,
E. Chiarparin,
E. Tamanini,
P. Pathuri,
J. Coyle,
Adam Hold,
F. Holding,
N. Amin,
Agnés C. L. Martin,
S. Rich,
...
V. Berdini,
J. Yon,
P. Acklam,
R. Burke,
L. Drouin,
J. Harmer,
F. Jeganathan,
R. V. van Montfort,
Yvette M Newbatt,
M. Tortorici,
Maura Westlake,
Amy Wood,
S. Hoelder,
T. Heightman
|
5 |
2016 |
5
🐜
|
|
🐬
|
Development of rationally designed DNA N6 adenine methyltransferase inhibitors.
Gerard Hobley,
Jennifer C. McKelvie,
J. Harmer,
J. Howe,
P. Oyston,
P. Roach
|
3 |
2012 |
3
🐬
|
|
🐬
|
Inhibition of Yersinia pestis DNA adenine methyltransferase in vitro by a stibonic acid compound: identification of a potential novel class of antimicrobial agents
J. McKelvie,
M. Richards,
J. Harmer,
TS Milne,
PL Roach,
Pcf Oyston
|
3 |
2013 |
3
🐬
|
|
🐜
|
Direct and continuous fluorescence-based measurements of Pyrococcus horikoshii DNA N-6 adenine methyltransferase activity.
9 auth.
Michael D. Maynard-Smith,
Jennifer C. McKelvie,
R. J. Wood,
J. Harmer,
Rohan T. Ranasinghe,
C. L. Williams,
...
Danielle M Coomber,
Alexandra F Stares,
P. Roach
|
1 |
2011 |
1
🐜
|
|
🐜
|
Correction: Corrigendum: Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability
23 auth.
K. Tatton-Brown,
S. Seal,
Elise Ruark,
J. Harmer,
Emma Ramsay,
Silvana del Vecchio Duarte,
A. Zachariou,
S. Hanks,
Eleanor M. O’Brien,
L. Aksglaede,
...
D. Baralle,
T. Dabir,
B. Gener,
D. Goudie,
T. Homfray,
Ajith Kumar,
D. Pilz,
A. Selicorni,
I. Temple,
L. Van Maldergem,
Naomi Yachelevich,
R. V. van Montfort,
N. Rahman
|
0 |
2014 |
0
🐜
|
|
🐬
|
Crystal structure of HydG: A maturase of the [FeFe]-hydrogenase
P. Dinis,
J. Harmer,
Rebecca C. Driesener,
P. Roach
|
0 |
2015 |
0
🐬
|
