|
🦁
|
Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1
10 auth.
H. Orr,
M. Chung,
S. Banfi,
T. Kwiatkowski,
A. Servadio,
A. Beaudet,
...
A. McCall,
L. Duvick,
L. Ranum,
H. Zoghbi
|
10 |
1993 |
10
🦁
|
|
🦁
|
Trinucleotide repeat disorders.
H. Orr,
H. Zoghbi
|
10 |
2007 |
10
🦁
|
|
🐢
|
Glutamine repeats and neurodegeneration.
H. Zoghbi,
H. Orr
|
10 |
2000 |
10
🐢
|
|
🐢
|
Ataxin-1 Nuclear Localization and Aggregation Role in Polyglutamine-Induced Disease in SCA1 Transgenic Mice
8 auth.
I. Klement,
P. Skinner,
M. D. Kaytor,
H. Yi,
S. Hersch,
H. Clark,
...
H. Zoghbi,
H. Orr
|
9 |
1998 |
9
🐢
|
|
🐜
|
Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14.
13 auth.
G. Schellenberg,
T. Bird,
E. Wijsman,
H. Orr,
L. Anderson,
E. Nemens,
J. White,
Lori L.C. Bonnycastle,
J. Weber,
M. Alonso,
...
H. Potter,
L. Heston,
G. Martin
|
9 |
1992 |
9
🐜
|
|
🐜
|
Identification of genes that modify ataxin-1-induced neurodegeneration
15 auth.
P. Fernandez-Funez,
M. L. Nino-Rosales,
B. Gouyon,
Wei-Chi She,
James M. Luchak,
P. Martinez,
E. Turiegano,
Jonathan Benito,
M. Capovilla,
P. Skinner,
...
A. McCall,
I. Canal,
H. Orr,
H. Zoghbi,
J. Botas
|
9 |
2000 |
9
🐜
|
|
🐜
|
RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia
10 auth.
Haibin Xia,
Q. Mao,
S. Eliason,
S. Harper,
Inês H Martins,
H. Orr,
...
H. Paulson,
Linda Yang,
R. Kotin,
B. Davidson
|
9 |
2004 |
9
🐜
|
|
🐢
|
SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat
9 auth.
E. Burright,
H. Clark,
A. Servadio,
T. Matilla,
R. Feddersen,
Wael S. Yunis,
...
L. Duvick,
H. Zoghbi,
H. Orr
|
9 |
1995 |
9
🐢
|
|
🐢
|
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
8 auth.
P. Skinner,
B. Koshy,
C. Cummings,
I. Klement,
K. Helin,
A. Servadio,
...
H. Zoghbi,
H. Orr
|
9 |
1997 |
9
🐢
|
|
🐬
|
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1
C. Cummings,
M. Mancini,
B. Antalffy,
D. DeFranco,
H. Orr,
H. Zoghbi
|
9 |
1998 |
9
🐬
|
|
🐜
|
Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice.
8 auth.
C. Cummings,
Yaling Sun,
P. Opal,
B. Antalffy,
R. Mestril,
H. Orr,
...
W. Dillmann,
H. Zoghbi
|
9 |
2001 |
9
🐜
|
|
🐜
|
Mutation of the E6-AP Ubiquitin Ligase Reduces Nuclear Inclusion Frequency While Accelerating Polyglutamine-Induced Pathology in SCA1 Mice
9 auth.
C. Cummings,
E. Reinstein,
Yaling Sun,
B. Antalffy,
Yong-hui Jiang,
A. Ciechanover,
...
H. Orr,
A. Beaudet,
H. Zoghbi
|
8 |
1999 |
8
🐜
|
|
🐢
|
Evidence for a mechanism predisposing to intergenerational CAG repeat instability in spinocerebellar ataxia type I
M. Chung,
L. Ranum,
L. Duvick,
A. Servadio,
H. Zoghbi,
H. Orr
|
8 |
1993 |
8
🐢
|
