π
|
Inhibition of the hedgehog pathway in advanced basal-cell carcinoma.
16 auth.
D. V. Von Hoff,
P. LoRusso,
C. Rudin,
J. Reddy,
R. Yauch,
R. Tibes,
G. Weiss,
M. Borad,
C. Hann,
J. Brahmer,
...
H. Mackey,
B. Lum,
W. Darbonne,
J. Marsters,
F. D. de Sauvage,
J. Low
|
10 |
2009 |
10 π
|
π
|
First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement.
28 auth.
J. Tabernero,
G. Shapiro,
P. LoRusso,
A. Cervantes,
G. Schwartz,
G. Weiss,
L. Paz-Ares,
D. Cho,
J. Infante,
M. Alsina,
M. Gounder,
R. Falzone,
Jamie Harrop,
A. C. White,
I. Toudjarska,
...
D. Bumcrot,
R. Meyers,
G. Hinkle,
N. Svrzikapa,
R. Hutabarat,
Valerie A. Clausen,
J. Cehelsky,
S. Nochur,
C. GambaβVitalo,
A. Vaishnaw,
D. Sah,
J. Gollob,
H. Burris
|
9 |
2013 |
9 π
|
π
|
Phase I Trial of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Refractory, Locally Advanced or Metastatic Solid Tumors
14 auth.
P. LoRusso,
C. Rudin,
J. Reddy,
R. Tibes,
G. Weiss,
M. Borad,
C. Hann,
J. Brahmer,
I. Chang,
W. Darbonne,
...
R. Graham,
K. Zerivitz,
J. Low,
D. V. Von Hoff
|
9 |
2011 |
9 π
|
π
|
Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.
40 auth.
W. Tap,
Z. Wainberg,
S. Anthony,
P. Ibrahim,
Chao Zhang,
J. Healey,
B. Chmielowski,
A. Staddon,
A. Cohn,
G. Shapiro,
V. Keedy,
Arun S. Singh,
I. Puzanov,
E. Kwak,
A. Wagner,
...
D. V. Von Hoff,
G. Weiss,
R. Ramanathan,
Jiazhong Zhang,
G. Habets,
Ying Zhang,
Elizabeth A. Burton,
G. Visor,
L. Sanftner,
P. Severson,
Hoa T. Nguyen,
Marie Kim,
A. Marimuthu,
Garson Tsang,
Rafe Shellooe,
Carolyn Gee,
B. West,
P. Hirth,
K. Nolop,
M. van de Rijn,
H. Hsu,
C. Peterfy,
P. Lin,
S. Tong-Starksen,
G. Bollag
|
8 |
2015 |
8 π
|
π
|
Activity and safety of brigatinib in ALK-rearranged non-small-cell lung cancer and other malignancies: a single-arm, open-label, phase 1/2 trial.
16 auth.
S. Gettinger,
L. Bazhenova,
C. Langer,
R. Salgia,
K. Gold,
R. Rosell,
A. Shaw,
G. Weiss,
M. Tugnait,
N. Narasimhan,
...
D. Dorer,
D. Kerstein,
V. Rivera,
T. Clackson,
F. Haluska,
D. Camidge
|
8 |
2016 |
8 π
|
π’
|
MicroRNAs and cancer: past, present, and potential future
K. M. Nelson,
G. Weiss
|
8 |
2008 |
8 π’
|
π’
|
miR-1254 and miR-574-5p: Serum-Based microRNA Biomarkers for Early-Stage Non-small Cell Lung Cancer
Kristen M. Foss,
Chao Sima,
D. Ugolini,
M. Neri,
Kristi E. Allen,
G. Weiss
|
8 |
2011 |
8 π’
|
π¦
|
EGFR regulation by microRNA in lung cancer: correlation with clinical response and survival to gefitinib and EGFR expression in cell lines.
13 auth.
G. Weiss,
L. Bemis,
E. Nakajima,
M. Sugita,
D. Birks,
W. Robinson,
M. Varella-Garcia,
P. Bunn,
J. Haney,
B. Helfrich,
...
H. Kato,
F. Hirsch,
W. Franklin
|
7 |
2008 |
7 π¦
|
π
|
Suramin: a novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer.
10 auth.
C. Myers,
M. Cooper,
C. Stein,
R. Larocca,
M. Walther,
G. Weiss,
...
P. Choyke,
N. Dawson,
S. Steinberg,
M. Uhrich
|
7 |
1992 |
7 π
|
π
|
Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors
14 auth.
D. V. Von Hoff,
M. Mita,
R. Ramanathan,
G. Weiss,
A. Mita,
P. LoRusso,
H. Burris,
L. Hart,
Susan Low,
Donald Parsons,
...
S. Zale,
J. Summa,
H. Youssoufian,
J. Sachdev
|
7 |
2016 |
7 π
|
π
|
First-in-human phase I study of copanlisib (BAY 80-6946), an intravenous pan-class I phosphatidylinositol 3-kinase inhibitor, in patients with advanced solid tumors and non-Hodgkin's lymphomas
21 auth.
A. Patnaik,
L. Appleman,
A. Tolcher,
K. Papadopoulos,
M. Beeram,
D. Rasco,
G. Weiss,
J. Sachdev,
M. Chadha,
Monica Fulk,
...
S. Ejadi,
J. Mountz,
M. Lotze,
F. Toledo,
E. Chu,
M. Jeffers,
C. PeΓ±a,
C. Xia,
S. Reif,
I. Genvresse,
R. Ramanathan
|
7 |
2016 |
7 π
|
π’
|
Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib.
8 auth.
A. Chang,
J. Solomon,
J. Hainsworth,
L. Goldberg,
E. McKenna,
B. Day,
...
Diana M. Chen,
G. Weiss
|
7 |
2014 |
7 π’
|