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An aged immune system drives senescence and ageing of solid organs
33 auth.
Matthew J. Yousefzadeh,
R. Flores,
Yi Zhu,
Zoe C. Schmiechen,
R. W. Brooks,
Christy E. Trussoni,
Yuxiang Cui,
Luise A Angelini,
Kyoo-a Lee,
S. McGowan,
Adam L. Burrack,
Dong Wang,
Qing D Dong,
A. Lu,
T. Sano,
...
Ryan D. O’Kelly,
Collin A McGuckian,
Jonathan I Kato,
Michael P. Bank,
Erin A. Wade,
S. Pillai,
J. Klug,
W. Ladiges,
C. Burd,
S. Lewis,
N. LaRusso,
N. Vo,
Yinsheng Wang,
E. Kelley,
J. Huard,
Ingunn M. Stromnes,
P. Robbins,
L. Niedernhofer
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9 |
2021 |
9 🐜
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NF-κB inhibition delays DNA damage-induced senescence and aging in mice.
19 auth.
J. Tilstra,
A. Robinson,
Jin Wang,
Siobhán Q. Gregg,
Cheryl L. Clauson,
D. Reay,
L. Nasto,
C. S. St Croix,
A. Usas,
N. Vo,
...
J. Huard,
P. Clemens,
D. Stolz,
D. Guttridge,
Simon C Watkins,
G. Garinis,
Yinsheng Wang,
L. Niedernhofer,
P. Robbins
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8 |
2012 |
8 🐜
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🦁
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Expression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degeneration.
N. Vo,
R. Hartman,
T. Yurube,
Lloydine J. Jacobs,
G. Sowa,
James D. Kang
|
8 |
2013 |
8 🦁
|
🦁
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Molecular mechanisms of biological aging in intervertebral discs
10 auth.
N. Vo,
R. Hartman,
P. Patil,
M. Risbud,
D. Kletsas,
J. Iatridis,
...
J. Hoyland,
C. L. Le Maitre,
G. Sowa,
James D. Kang
|
8 |
2016 |
8 🦁
|
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Molecular Basis of Intervertebral Disc Degeneration and Herniations: What Are the Important Translational Questions?
Tiffany R. Kadow,
G. Sowa,
N. Vo,
James D. Kang
|
7 |
2015 |
7 🐬
|
🐬
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Inflammatory and catabolic signalling in intervertebral discs: the roles of NF-κB and MAP kinases.
K. Wuertz,
N. Vo,
D. Kletsas,
N. Boos
|
7 |
2012 |
7 🐬
|
🐢
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Mitochondrial‐derived reactive oxygen species (ROS) play a causal role in aging‐related intervertebral disc degeneration
13 auth.
L. Nasto,
A. Robinson,
Kevin Ngo,
Cheryl L. Clauson,
Qing D Dong,
C. S. St Croix,
G. Sowa,
E. Pola,
P. Robbins,
James D. Kang,
...
L. Niedernhofer,
P. Wipf,
N. Vo
|
7 |
2013 |
7 🐢
|
🐢
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Systemic clearance of p16INK4a‐positive senescent cells mitigates age‐associated intervertebral disc degeneration
14 auth.
P. Patil,
Qing D Dong,
Dong Wang,
Jianhui Chang,
Christopher D. Wiley,
M. Demaria,
Joon Y. Lee,
James D. Kang,
L. Niedernhofer,
P. Robbins,
...
G. Sowa,
J. Campisi,
Daohong Zhou,
N. Vo
|
6 |
2019 |
6 🐢
|
🐜
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p38 MAPK Inhibition in Nucleus Pulposus Cells: A Potential Target for Treating Intervertebral Disc Degeneration
7 auth.
R. Studer,
A. Aboka,
L. Gilbertson,
H. Georgescu,
G. Sowa,
N. Vo,
...
James D. Kang
|
6 |
2007 |
6 🐜
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Injection of AAV2-BMP2 and AAV2-TIMP1 into the nucleus pulposus slows the course of intervertebral disc degeneration in an in vivo rabbit model.
13 auth.
S. Leckie,
B. Bechara,
R. Hartman,
G. Sowa,
B. Woods,
J. P. Coelho,
William T. Witt,
Qing D Dong,
B. W. Bowman,
Kevin M. Bell,
...
N. Vo,
B. Wang,
James D. Kang
|
6 |
2012 |
6 🐜
|
🐜
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Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging
42 auth.
A. Robinson,
Matthew J. Yousefzadeh,
Tania A. Rozgaja,
Jin Wang,
Xuesen Li,
J. Tilstra,
C. H. Feldman,
Siobhán Q. Gregg,
C. Johnson,
Erin M. Skoda,
Marie-Céline Frantz,
Harris Bell-Temin,
Hannah Pope-Varsalona,
Aditi U. Gurkar,
L. Nasto,
...
R. A. Robinson,
Heike Fuhrmann-Stroissnigg,
J. Czerwinska,
S. McGowan,
Nadiezhda Cantú-Medellín,
J. Harris,
Salony Maniar,
M. Ross,
Christy E. Trussoni,
N. LaRusso,
Eugenia Cifuentes-Pagano,
P. Pagano,
B. Tudek,
N. Vo,
L. Rigatti,
P. Opresko,
D. Stolz,
Simon C Watkins,
C. Burd,
C. S. Croix,
G. Siuzdak,
N. Yates,
P. Robbins,
Yinsheng Wang,
P. Wipf,
E. Kelley,
L. Niedernhofer
|
6 |
2018 |
6 🐜
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