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🐜
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Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells.
8 auth.
F. Trettel,
D. Rigamonti,
Paige Hilditch-Maguire,
V. Wheeler,
A. Sharp,
F. Persichetti,
...
E. Cattaneo,
M. MacDonald
|
9 |
2000 |
9
🐜
|
|
🐜
|
Identification of Genetic Factors that Modify Clinical Onset of Huntington’s Disease
27 auth.
Jong-Min Lee,
V. Wheeler,
M. Chao,
J. Vonsattel,
R. M. Pinto,
D. Lucente,
K. Abu-Elneel,
E. Ramos,
J. Mysore,
T. Gillis,
M. MacDonald,
J. Gusella,
D. Harold,
T. Stone,
V. Escott-Price,
...
Jun Han,
Alexey Vedernikov,
P. Holmans,
L. Jones,
S. Kwak,
Mithra Mahmoudi,
M. Orth,
G. Landwehrmeyer,
Jane S. Paulsen,
E. Dorsey,
I. Shoulson,
R. Myers
|
8 |
2015 |
8
🐜
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|
🦁
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Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.
14 auth.
V. Wheeler,
Jacqueline K. White,
C. Gutekunst,
V. Vrbanac,
Meredith Weaver,
Xiao-Jiang Li,
Shihua Li,
Hong Yi,
J. Vonsattel,
J. Gusella,
...
S. Hersch,
W. Auerbach,
A. Joyner,
M. MacDonald
|
8 |
2000 |
8
🦁
|
|
🐜
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Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes.
58 auth.
Virginia B. Mattis,
Soshana P Svendsen,
A. Ebert,
C. Svendsen,
Alvin R. King,
M. Casale,
S. Winokur,
G. Batugedara,
M. Vawter,
P. Donovan,
L. Lock,
L. Thompson,
Yu Zhu,
E. Fossale,
R. S. Atwal,
...
T. Gillis,
J. Mysore,
Jian Li,
I. Seong,
Yiping Shen,
Xiaoli Chen,
V. Wheeler,
M. MacDonald,
J. Gusella,
S. Akimov,
N. Arbez,
T. Juopperi,
T. Ratovitski,
J. Chiang,
Woon Kim,
E. Chighladze,
E. Watkin,
C. Zhong,
G. Makri,
R. Cole,
R. Margolis,
Hongjun Song,
G. Ming,
C. Ross,
J. Kaye,
Aaron Daub,
Punita Sharma,
A. Mason,
S. Finkbeiner,
Junying Yu,
J. Thomson,
D. Rushton,
S. Brazier,
A. Battersby,
A. Redfern,
H. Tseng,
A. W. J. Harrison,
P. Kemp,
N. Allen,
M. Onorati,
V. Castiglioni,
E. Cattaneo,
J. Arjomand
|
8 |
2012 |
8
🐜
|
|
🦁
|
Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse.
12 auth.
V. Wheeler,
W. Auerbach,
Jacqueline K. White,
J. Srinidhi,
A. Auerbach,
Angela Ryan,
...
M. Duyao,
V. Vrbanac,
Meredith Weaver,
J. Gusella,
A. Joyner,
M. MacDonald
|
8 |
1999 |
8
🦁
|
|
🐜
|
Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models
18 auth.
L. Menalled,
B. El-Khodor,
Monica Patry,
M. Suárez-Fariñas,
Samantha J. Orenstein,
Benjamin Zahasky,
Christina Leahy,
V. Wheeler,
X. W. Yang,
M. MacDonald,
...
A. Morton,
G. Bates,
Janet Leeds,
L. Park,
D. Howland,
E. Signer,
A. Tobin,
D. Brunner
|
8 |
2009 |
8
🐜
|
|
🐢
|
Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset.
7 auth.
M. Swami,
A. Hendricks,
T. Gillis,
T. Massood,
J. Mysore,
R. Myers,
...
V. Wheeler
|
8 |
2009 |
8
🐢
|
|
🐜
|
Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice.
9 auth.
S. Ginés,
I. Seong,
E. Fossale,
Elena V. Ivanova,
F. Trettel,
J. Gusella,
...
V. Wheeler,
F. Persichetti,
M. MacDonald
|
8 |
2003 |
8
🐜
|
|
🦁
|
Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum.
V. Wheeler,
Lori-Anne Lebel,
V. Vrbanac,
Allison M Teed,
H. te Riele,
M. MacDonald
|
7 |
2003 |
7
🦁
|
|
🐢
|
Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes
11 auth.
E. Dragileva,
A. Hendricks,
Allison M Teed,
T. Gillis,
Edith T. Lopez,
E. Friedberg,
...
R. Kucherlapati,
W. Edelmann,
K. Lunetta,
M. MacDonald,
V. Wheeler
|
7 |
2009 |
7
🐢
|
|
🐢
|
Mismatch Repair Genes Mlh1 and Mlh3 Modify CAG Instability in Huntington's Disease Mice: Genome-Wide and Candidate Approaches
16 auth.
R. M. Pinto,
E. Dragileva,
Andrew W. Kirby,
Alejandro Lloret,
Edith T. Lopez,
Jason St. Claire,
G. Panigrahi,
C. Hou,
K. Holloway,
T. Gillis,
...
Jolene R. Guide,
P. Cohen,
Guo-Min Li,
C. E. Pearson,
M. Daly,
V. Wheeler
|
7 |
2013 |
7
🐢
|
|
🐜
|
Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport
10 auth.
Fátima Gasset‐Rosa,
Carlos Chillón-Marinas,
A. Goginashvili,
R. S. Atwal,
Jonathan W. Artates,
Ricardos Tabet,
...
V. Wheeler,
A. Bang,
D. Cleveland,
C. Lagier-Tourenne
|
7 |
2017 |
7
🐜
|
