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Stratified analyses refine association between TLR7 rare variants and severe COVID-19
1591 auth.
Jannik Boos,
C. I. van der Made,
Gayatri Ramakrishnan,
Eamon Coughlan,
Rosanna Asselta,
B. Löscher,
Luca V.C. Valenti,
R. de Cid,
Luís Bujanda,
Antonio Julià,
E. Pairo-Castineira,
J. Baillie,
Sandra May,
Berina Zametica,
Julia Heggemann,
...
A. Albillos,
J. Banales,
Jordi Barretina,
Natàlia Blay,
Paolo Bonfanti,
Maria Buti,
Javier Fernández,
S. Marsal,
D. Prati,
L. Ronzoni,
N. Sacchi,
V. Rimoldi,
E. Paraboschi,
A. Bandera,
Flora Peyvandi,
Giacomo Grasselli,
Francesco Blasi,
F. Malvestiti,
S. Pelusi,
C. Bianco,
Lorenzo Miano,
Angela Lombardi,
Pietro Invernizzi,
A. Gerussi,
G. Citerio,
Andrea Biondi,
M. Valsecchi,
M. Cazzaniga,
Giuseppe Foti,
I. Beretta,
M. D'Angiò,
L. Bettini,
X. Farré,
Susana Iraola-Guzmán,
Manolis Kogevinas,
Gemma Castaño-Vinyals,
K. García-Etxebarría,
B. Nafría,
Mauro D'Amato,
A. Palom,
Colin D. Begg,
S. Clohisey,
Charles Hinds,
P. Horby,
Julian Knight,
Lowell Ling,
D. Maslove,
D. McAuley,
J. Millar,
Hugh Montgomery,
Alistair Nichol,
P. Openshaw,
Alexandre C Pereira,
C. Ponting,
K. Rowan,
M. Semple,
M. Shankar-Hari,
C. Summers,
Timothy Walsh,
J. Baillie,
Latha Aravindan,
Ruth-Ann Armstrong,
Heather Biggs,
Ceilia Boz,
A. Brown,
R. Clark,
A. Coutts,
J. Coyle,
Louise Cullum,
Sukamal Das,
Nicky Day,
Lorna Donnelly,
Esther Duncan,
A. Fawkes,
Paul Fineran,
M. Fourman,
A. Furlong,
J. Furniss,
B. Gallagher,
T. Gilchrist,
A. Golightly,
Fiona Griffiths,
K. Hafezi,
Debbie Hamilton,
Ross Hendry,
Andrew Law,
D. Law,
Rachel Law,
Sarah Law,
R. Lidstone-Scott,
L. Macgillivray,
Alan Maclean,
Hanning Mal,
Sarah McCafferty,
E. Mcmaster,
Jen Meikle,
S. Moore,
K. Morrice,
L. Murphy,
Sheena Murphy,
Mybaya Hellen,
W. Oosthuyzen,
Chenqing Zheng,
Jiantao Chen,
Nicholas Parkinson,
Trevor Paterson,
Katherine Schon,
Andy Stenhouse,
Mihaela Das,
Maaike C Swets,
Helen Szoor-McElhinney,
Filip Taneski,
L. Turtle,
Tony Wackett,
Mairi Ward,
J. Weaver,
N. Wrobel,
M. Zechner,
G. Arbane,
A. Bociek,
S. Campos,
Neus Grau,
Tim Owen Jones,
Rosario Lim,
Martina Marotti,
M. Ostermann,
Christopher Whitton,
Z. Alldis,
R. Astin-Chamberlain,
F. Bibi,
J. Biddle,
S. Blow,
M. Bolton,
Catherine Borra,
Ruth Bowles,
Maudrian Burton,
Y. Choudhury,
David Collier,
Amber Cox,
A. Easthope,
P. Ebano,
Stavros Fotiadis,
J. Gurasashvili,
Rosslyn Halls,
Pippa Hartridge,
D. Kallon,
J. Kassam,
I. Lancoma-Malcolm,
Maninderpal Matharu,
P. May,
O. Mitchelmore,
Tabitha Newman,
Mital Patel,
J.M. Pheby,
Irene Pinzuti,
Z. Prime,
O. Prysyazhna,
Julian Shiel,
Melanie Taylor,
C. Tierney,
S. Wood,
A. Żak,
O. Zongo,
Stephen Bonner,
K. Hugill,
Jessica Jones,
Steven Liggett,
Evie Headlam,
N. Bandla,
M. Gellamucho,
Michelle Davies,
Christopher Thompson,
M. Abdelrazik,
D. Bakthavatsalam,
M. Elhassan,
A. Ganesan,
A. Haldeos,
J. Moreno-Cuesta,
D. Purohit,
R. Vincent,
K. Xavier,
Kumar Rohit,
Frater Alasdair,
Malik Saleem,
C. David,
Jenkins Samuel,
Z. Lamond,
Wall Alanna,
Jaime Fernandez-Roman,
David O. Hamilton,
Emily Johnson,
Brian Johnston,
M. Martinez,
Suleman Mulla,
David Shaw,
Alicia A. C. Waite,
V. Waugh,
I. Welters,
Karen Williams,
A. Cavazza,
Maeve Cockrell,
Eleanor Corcoran,
M. Depante,
C. Finney,
E. Jerome,
M. Mcphail,
Monalisa Nayak,
H. Noble,
Kevin O’Reilly,
Evita Pappa,
Rohit Saha,
Sian Saha,
John Smith,
A. Knighton,
David Antcliffe,
D. Banach,
Stephen Brett,
Phoebe Coghlan,
Z. Fernandez,
Anthony Gordon,
Roceld Rojo,
S. Arias,
Maie Templeton,
M. Meredith,
L. Morris,
L. Ryan,
Amy Clark,
J. Sampson,
C. Peters,
M. Dent,
M. Langley,
Saima Ashraf,
S. Wei,
Angela Andrew,
A. Bashyal,
N. Davidson,
P. Hutton,
S. McKechnie,
Jean Wilson,
David Baptista,
Rebecca Crowe,
Rita Fernandes,
R. Herdman-Grant,
Anna Joseph,
Denise O’Connor,
Meryem Allen,
Adam Loveridge,
India Mckenley,
Eriko Morino,
Andrés Naranjo,
R. Simms,
K. Sollesta,
A. Swain,
H. Venkatesh,
J. Khera,
Jonathan Fox,
G. Andrew,
L. Barclay,
M. Callaghan,
R. Campbell,
Sarah Clark,
Dave Hope,
L. Marshall,
Corrienne Mcculloch,
Kate Briton,
Joseph A. Singleton,
Sohphie Birch,
L. Brimfield,
Z. Daly,
D. Pogson,
S. Rose,
Ceri Battle,
E. Brinkworth,
R. Harford,
C. Murphy,
Luke Newey,
T. Rees,
Marie Williams,
Sophie Arnold,
P. Polgarova,
Katerina Stroud,
Eoghan D Meaney,
Megan Jones,
A. Ng,
Shruti Agrawal,
N. Pathan,
Deborah White,
Esther Daubney,
Kayla Elston,
L. Grauslyte,
Musarat Hussain,
M. Phull,
T. Pogreban,
L. Rosaroso,
E. Šalčiūtė,
George Franke,
Joanna Wong,
A. George,
L. Ortiz-Ruiz de Gordoa,
E. Peasgood,
Claire Phillips,
M. Bates,
J. Dasgin,
Jaspret Gill,
A. Nilsson,
James Scriven,
C. Delgado,
Deborah Dawson,
Lijun Ding,
Georgia Durrant,
O. Ezeobu,
S. Farnell-Ward,
Abiola Harrison,
Rebecca Kanu,
Susannah Leaver,
E. Maccacari,
Soumendu Manna,
R. Saluzzio,
Joana Queiroz,
T. Samakomva,
Christine Sicat,
J. Texeira,
Edna Fernandes Da Gloria,
A. Lisboa,
J. Rawlins,
Jisha Mathew,
Ashley Kinch,
William Hurt,
Nirav Shah,
Victoria Clark,
Maria Thanasi,
Nikki Yun,
Kamal Patel,
S. Bennett,
Emma Goodwin,
Matthew Jackson,
A. Kent,
C. Tibke,
W. Woodyatt,
Ahmed Zaki,
A. Abraheem,
P. Bamford,
K. Cawley,
Charlotte J. Dunmore,
M. Faulkner,
R. Girach,
H. Jeffrey,
Rhianna Jones,
Emily London,
I. Nagra,
F. Nasir,
Hannah Sainsbury,
C. Smedley,
Tahera Patel,
Matthew Smith,
S. Chukkambotla,
Aayesha Kazi,
J. Hartley,
Joseph Dykes,
Muhammad Hijazi,
Sarah Keith,
Meherunnisa Khan,
J. Ryan-Smith,
P. Springle,
Jacqueline Thomas,
N. Truman,
Samuel Saad,
Dabheoc Coleman,
Christopher Fine,
Roseanna Matt,
Bethan Gay,
Jack Dalziel,
Syamlan Ali,
Drew Goodchild,
Rhiannan Harling,
Ravi Bhatterjee,
W. Goddard,
C. Davison,
Stephen Duberly,
Jeanette Hargreaves,
Rachel Bolton,
Miriam Davey,
David Golden,
R. Seaman,
S. Cherian,
S. Cutler,
A. Heron,
A. Roynon-Reed,
T. Szakmany,
Gemma Williams,
O. Richards,
Y. Cheema,
Hollie Brooke,
S. Buckley,
J. C. Suarez,
R. Charlesworth,
Karen Hansson,
John Norris,
A. Poole,
A. Rose,
Rajdeep S Sandhu,
B. Sloan,
Elizabeth Smithson,
M. Thirumaran,
V. Wagstaff,
A. Metcalfe,
Mark Brunton,
J. Caterson,
H. Coles,
M. Frise,
S. Rai,
N. Jacques,
Liza Keating,
E. Tilney,
S. Bartley,
P. Bhuie,
S. Gibson,
A. Lyle,
F. McNeela,
J. Radhakrishnan,
A. Hughes,
B. Yates,
Jessica Reynolds,
H. Campbell,
Maria Thompsom,
S. Dodds,
Stacey Duffy,
S. Greer,
K. Shuker,
A. Tridente,
R. Khade,
Ashok Sundar,
G. Tsinaslanidis,
Isobel Birkinshaw,
Joseph Carter,
K. Howard,
Joanne Ingham,
Rosie Joy,
H. Pearson,
S. Roche,
Zoe Scott,
H. Bancroft,
M. Bellamy,
M. Carmody,
J. Daglish,
F. Moore,
Joanne Rhodes,
M. Sangombe,
S. Kadiri,
M. Croft,
I. White,
V. Frost,
M. Aquino,
Rajeev Jha,
Vinodh Krishnamurthy,
L. Lim,
Li Lim,
E. Combes,
T. Joefield,
S. Monnery,
Valerie Beech,
Sallyanne Trotman,
C. Almaden-Boyle,
P. Austin,
L. Cabrelli,
Stephen Cole,
Matt Casey,
Susan Chapman,
C. Whyte,
Y. Baird,
Aaron Butler,
I. Chadbourn,
L. Folkes,
H. Fox,
Amy Gardner,
Raquel Gomez,
G. Hobden,
L. Hodgson,
K. King,
M. Margarson,
T. Martindale,
E. Meadows,
D. Raynard,
Y. Thirlwall,
David P. Helm,
J. Margalef,
K. Criste,
Rebecca Cusack,
K. Golder,
H. Golding,
Oliver Jones,
Samantha Leggett,
Michelle Male,
Martyna Marani,
Kirsty Prager,
T. Williams,
B. Roberts,
Karen Salmon,
P. Anderson,
Katie Archer,
K. Austin,
Caroline Davis,
A. Durie,
O. Kelsall,
J. Thrush,
Charlie Vigurs,
L. Wild,
H. Wood,
H. Tranter,
Alison Harrison,
Nicholas Cowley,
M. Mcalindon,
A. Burtenshaw,
S. Digby,
Emma Low,
Aled Morgan,
N. Cother,
Toby Rankin,
Sarah Clayton,
Alexander McCurdy,
C. Ahmed,
Balvinder Baines,
S. Clamp,
J. Colley,
Risna Haq,
A. Hayes,
J. Hulme,
S. Hussain,
S. Joseph,
Rita Kumar,
Zahira Maqsood,
Manjit Purewal,
L. Benham,
Z. Bradshaw,
Joann S Brown,
M. Caswell,
J. Cupitt,
Sarah Melling,
S. Preston,
N. Slawson,
E. Stoddard,
Scott A Warden,
B. Deacon,
C. Lynch,
C. Pothecary,
L. Roche,
G. S. Howe,
Jayaprakash Singh,
Keri Turner,
Hannah Ellis,
N. Stroud,
Jodie Hunt,
Joy Dearden,
E. Dobson,
Andy Drummond,
M. Mulcahy,
S. Munt,
G. O'Connor,
J. Philbin,
C. Rishton,
R. Tully,
Sarah Winnard,
S. Cathcart,
K. Duffy,
A. Puxty,
K. Puxty,
L. Turner,
J. Ireland,
G. Semple,
Kate Long,
S. Whiteley,
E. Wilby,
Bethan Ogg,
A. Cowton,
A. Kay,
M. Kent,
K. Potts,
Ami Wilkinson,
Suzanne Campbell,
Ellen Brown,
J. Melville,
J. Naisbitt,
R. Joseph,
M. Lazo,
O. Walton,
A. Neal,
Peter D G Alexander,
Schvearn Allen,
J. Bradley-Potts,
C. Brantwood,
J. Egan,
T. Felton,
G. Padden,
L. Ward,
S. Moss,
S. Glasgow,
Lynn Abel,
Michael Brett,
B. Digby,
Lisa Gemmell,
J. Hornsby,
P. MacGoey,
P. O'Neil,
Richard Price,
N. Rodden,
K. Rooney,
R. Sundaram,
Nicola Thomson,
B. Hopkins,
L. Thrasyvoulou,
Heather Willis,
Martyn Clark,
M. Coulding,
E. Jude,
J. McCormick,
O. Mercer,
D. Potla,
H. Rehman,
H. Savill,
V. Turner,
C. Downes,
K. Holding,
K. Riches,
Mary Hilton,
M. Hayman,
Deepak Subramanian,
P. Daniel,
O. Adanini,
N. Bhatia,
Maines Msiska,
Rebecca Collins,
I. Clement,
Bijal Patel,
A. Gulati,
C. Hays,
K. Webster,
Anne Hudson,
Andrea Webster,
E. Stephenson,
L. Mccormack,
Victoria Slater,
R. Nixon,
H. Hanson,
Maggie Fearby,
S. Kelly,
Victoria Bridgett,
Philip Robinson,
J. Camsooksai,
C. Humphrey,
S. Jenkins,
H. Reschreiter,
B. Wadams,
Yasmin Death,
V. Bastion,
Daphene Clarke,
Beena David,
H. Kent,
R. Lorusso,
G. Lubimbi,
S. Murdoch,
M. Penacerrada,
Alastair Thomas,
J. Valentine,
A. Vochin,
R. Wulandari,
B. Djeugam,
G. Bell,
K. English,
Amro Katary,
L. Wilcox,
M. Bruce,
K. Connolly,
Tracey Duncan,
H. T-Michael,
G. Lindergard,
S. Hey,
C. Fox,
Jordan Alfonso,
L. Durrans,
J. Guerin,
B. Blackledge,
Jade D. Harris,
M. Hruska,
Ayaa Eltayeb,
T. Lamb,
T. Hodgkiss,
Lisa Cooper,
J. Rothwell,
A. Allan,
Felicity Anderson,
C. Kaye,
J. Liew,
J. Medhora,
Teresa Scott,
E. Trumper,
A. Botello,
L. Lankester,
N. Nikitas,
Colin Wells,
Bethan Stowe,
Kayleigh Spencer,
C. Brandwood,
Lara Smith,
Katie Birchall,
Laurel Kolakaluri,
Deborah Baines,
A. Sukumaran,
E. Apetri,
C. Basikolo,
L. Catlow,
B. Charles,
P. Dark,
R. Doonan,
Alice Harvey,
Daniel Horner,
K. Knowles,
Stephanie Lee,
D. Lomas,
Chloe Lyons,
T. Marsden,
D. Mclaughlan,
L. McMorrow,
J. Pendlebury,
J. Perez,
M. Poulaka,
Nicola Proudfoot,
Melanie Slaughter,
K. Slevin,
V. Thomas,
Danielle R. Walker,
Angiy Michael,
M. Collis,
T. Cosier,
Gemma Millen,
Neil Richardson,
N. Schumacher,
H. Weston,
J. Rand,
N. Baxter,
S. Henderson,
S. Kennedy-Hay,
C. McParland,
Laura Rooney,
Malcolm Sim,
G. McCreath,
L. Akeroyd,
Shereen Bano,
Matt Bromley,
Lucy Gurr,
Tom Lawton,
James Morgan,
Kirsten Sellick,
Deborah Warren,
Brian Wilkinson,
J. McGowan,
Camilla Ledgard,
A. Stacey,
K. Pye,
Ruth Bellwood,
Michael Bentley,
J. Bewley,
Z. Garland,
L. Grimmer,
B. Gumbrill,
Rebekah Johnson,
K. Sweet,
Denise Webster,
Georgia Efford,
K. Convery,
Deirdre Fottrell-gould,
L. Hudig,
J. Keshet-price,
G. Randell,
K. Stammers,
M. Bokhari,
V. Linnett,
Rachael Lucas,
W. McCormick,
J. Ritzema,
A. Sanderson,
H. Wild,
A. Rostron,
Alistair Roy,
Lindsey Woods,
Sarah Cornell,
F. Wakinshaw,
Kimberley Rogerson,
Jordan Jarmain,
Robert Parker,
Amie Reddy,
I. Turner-bone,
L. Wilding,
P. Harding,
C. Abernathy,
L. Foster,
A. Gratrix,
V. Martinson,
Priyai Parkinson,
Elizabeth Stones,
Llucia Carbral-Ortega,
G. Bercades,
David Brealey,
I. Hass,
Niall MacCallum,
G. Martir,
E. Raith,
Anna Reyes,
Deborah Smyth,
L. Zitter,
S. Benyon,
S. Marriott,
Linda Park,
S. Keenan,
Elizabeth Gordon,
Helen Quinn,
Kizzy Baines,
L. Cagova,
A. Fofano,
L. Garner,
Helen Holcombe,
S. Mepham,
A. M. Mitchell,
L. Mwaura,
K. Praman,
A. Vuylsteke,
J. Zamikula,
B. Purewal,
V. Rivers,
S. Bell,
Hayley Blakemore,
B. Borislavova,
B. Faulkner,
E. Gendall,
E. Goff,
K. Hayes,
Matt Thomas,
R. Worner,
Kerry Smith,
D. Stephens,
L. Mew,
E. Mwaura,
R. Stewart,
Felicity Williams,
L. Wren,
S. Sutherland,
E. Bevan,
Jane Martin,
D. Trodd,
G. Watson,
C. Brown,
Amy Collins,
W. Khaliq,
E. T. Gude,
O. Akinkugbe,
A. Bamford,
Emily Beech,
H. Belfield,
Michael Bell,
Charlene Davies,
Gareth A. L. Jones,
T. McHugh,
H. Meghari,
Lauran O’Neill,
Mark Peters,
Samiran Ray,
A. Tomas,
Iona Burn,
Geraldine Hambrook,
K. Manso,
R. Penn,
P. Shanmugasundaram,
J. Tebbutt,
D. Thornton,
J. Cole,
Rhys Davies,
D. Duffin,
H. Hill,
Ben Player,
Emma Thomas,
Angharad Williams,
Denise Griffin,
N. Muchenje,
M. Mupudzi,
R. Partridge,
J. Conyngham,
Rachel Thomas,
Mary Wright,
Maria Alvarez Corral,
R. Jacob,
Cathy Jones,
C. Denmade,
S. Beavis,
K. Dale,
R. Gascoyne,
J. Hawes,
Kelly Pritchard,
L. Stevenson,
A. Whileman,
P. Doble,
Joanne Hutter,
C. Pawley,
C. Shovelton,
M. Vaida,
D. Butcher,
Susie O’Sullivan,
N. Butterworth-Cowin,
Norfaizan Ahmad,
J. Barker,
K. Bauchmuller,
S. Bird,
K. Cawthron,
K. Harrington,
Yvonne Jackson,
F. Kibutu,
B. Lenagh,
Shamiso Masuko,
Gary H. Mills,
A. Raithatha,
Matthew Wiles,
J. Willson,
H. Newell,
A. Lye,
L. Nwafor,
C. Jarman,
Sarah L Rowland-Jones,
David N. Foote,
Joby Cole,
Roger Thompson,
J. Watson,
Lisa Hesseldon,
I. Macharia,
Luke Chetam,
Jacqui Smith,
Amber Ford,
Samantha Anderson,
K. Birchall,
K. Housley,
Sara J. Walker,
L. Milner,
H. Hanratty,
H. Trower,
Patrick Phillips,
Simon Oxspring,
B. Donne,
C. Jardine,
Dewi Williams,
Alasdair Hay,
Rebecca Flanagan,
G. Hughes,
S. Latham,
Emma McKenna,
Jennifer Anderson,
R. Hull,
K. Rhead,
Carina Cruz,
Natalie Pattison,
R. Charnock,
D. McFarland,
D. Cosgrove,
Ashar Ahmed,
A. Morris,
Srinivas Jakkula,
Asifa Ali,
Megan Brady,
S. Dale,
Annalisa Dance,
L. Gledhill,
J. Greig,
K. Hanson,
K. Holdroyd,
M. Home,
D. Kelly,
Ross Kitson,
L. Matapure,
Deborah Melia,
S. Mellor,
T. Nortcliffe,
Jez Pinnell,
M. Robinson,
L. Shaw,
Ryan Shaw,
L. Thomis,
A. Wilson,
T. Wood,
L. Bayo,
E. Merwaha,
Tahira Ishaq,
Sarah Hanley,
M. Hibbert,
D. Tetla,
Chrsitopher Woodford,
Latha Durga,
Gareth Kennard-Holden,
D. Branney,
Jordan Frankham,
S. Pitts,
N. White,
S. Laha,
M. Verlander,
Alexandra Williams,
A. Altabaibeh,
A. Alvaro,
K. Gilbert,
Louise Ma,
L. Mostoles,
Chetana Parmar,
Kathryn Simpson,
C. Jetha,
Lauren Booker,
A. Pratley,
Colene Adams,
A. Agasou,
Tracie Arden,
Amy L. Bowes,
P. Boyle,
Mandy Beekes,
H. Button,
N. Capps,
M. Carnahan,
Anne Carter,
Danielle Childs,
D. Donaldson,
K. Hard,
F. Hurford,
Y. Hussain,
A. Javaid,
James Jones,
S. Jose,
Michael Leigh,
Terry Martin,
H. Millward,
N. Motherwell,
R. Rikunenko,
J. Stickley,
Julie Summers,
L. Ting,
H. Tivenan,
L. Tonks,
Rebecca Wilcox,
M. Holland,
N. Keenan,
Marc Lyons,
H. Wassall,
Chris Marsh,
Mervin Mahenthran,
Emma Carter,
Thomas Kong,
H. Blackman,
B. Creagh-Brown,
S. Donlon,
N. Michalak-Glinska,
S. Mtuwa,
V. Pristopan,
A. Salberg,
Eleanor Smith,
S. Stone,
C. Piercy,
J. Verula,
D. Burda,
Rugia Montaser,
L. Harden,
Irving Mayangao,
C. Marriott,
Paul Bradley,
C. Harris,
Susan Anderson,
Eleanor Andrews,
J. Birch,
Emma M Collins,
K. Hammerton,
R. O’Leary,
Michele Clark,
S. Purvis,
R. Barber,
C. Hewitt,
A. Hilldrith,
K. Jackson-Lawrence,
Sarah Shepardson,
Maryanne Wills,
Susan Butler,
Silvia Tavares,
Amy Cunningham,
Julia Hindale,
Sarwat Arif,
Sarah Bean,
K. Burt,
Michael Spivey,
C. Demetriou,
Charlotte Eckbad,
S. Hierons,
L. Howie,
S. Mitchard,
Lidia Ramos,
A. Serrano-Ruiz,
K. White,
F. Kelly,
D. Cristiano,
N. Dormand,
Zohreh Farzad,
M. Gummadi,
K. Liyanage,
Brijesh Patel,
Sara Salmi,
G. Sloane,
V. Thwaites,
M. Varghese,
A. C. Zborowski,
J. Allan,
T. Geary,
Gordon Houston,
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