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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
1795 auth.
Michael Brauer,
Gregory A. Roth,
Aleksandr Aravkin,
P. Zheng,
K. H. Abate,
Y. Abate,
C. Abbafati,
Rouzbeh Abbasgholizadeh,
Madineh Akram Abbasi,
Mohammadreza Abbasian,
M. Abbasifard,
M. Abbasi-Kangevari,
S. ElHafeez,
S. Abd-Elsalam,
Parsa Abdi,
...
Mohammad Abdollahi,
Meriem Abdoun,
Deldar Morad Abdulah,
Auwal Abdullahi,
Mesfin Abebe,
Aidin Abedi,
Armita Abedi,
Tadesse M. Abegaz,
Roberto Ariel Abeldaño Zuñiga,
Olumide Abiodun,
Temesgen Lera Abiso,
R. Aboagye,
Hassan Abolhassani,
M. Abouzid,
Girma Beressa Aboye,
Lucas Guimarães Abreu,
Hasan Abualruz,
Bilyaminu Abubakar,
Eman Abu-Gharbieh,
H. J. Abukhadijah,
Salahdein Aburuz,
A. Abu-Zaid,
M. M. Adane,
Isaac Yeboah Addo,
Giovanni Addolorato,
R. Adedoyin,
Victor Adekanmbi,
Bashir Aden,
J. B. Adetunji,
T. Adeyeoluwa,
Rishan Adha,
A. Adibi,
Qorinah Estiningtyas Sakilah Adnani,
Leticia Akua Adzigbli,
A. Afolabi,
R. Afolabi,
A. Afshin,
Shadi Afyouni,
M. Afzal,
Saira Afzal,
S. B. Agampodi,
Faith Agbozo,
Shahin Aghamiri,
A. Agodi,
Anurag Agrawal,
Williams Agyemang-Duah,
B. Ahinkorah,
Aqeel Ahmad,
Danish Ahmad,
Firdos Ahmad,
Noah Ahmad,
Shahzaib Ahmad,
Tauseef Ahmad,
Ali Ahmed,
Anisuddin Ahmed,
Ayman Ahmed,
Luai A Ahmed,
M. Ahmed,
Safoora Ahmed,
Syed Anees Ahmed,
Marjan Ajami,
G. T. Akalu,
Essona Matatom Akara,
Hossein Akbarialiabad,
Shiva Akhlaghi,
K. Akinosoglou,
Tomi F Akinyemiju,
Mohammed Ahmed Akkaif,
S. Akkala,
B. Akombi-Inyang,
S. Awaidy,
Syed Mahfuz Al Hasan,
Fares Alahdab,
T. AL-Ahdal,
Samer O. Alalalmeh,
T. Alalwan,
Z. Al-Aly,
K. Alam,
Nazmul Alam,
Fahad Mashhour Alanezi,
Turki M. Alanzi,
Almaza a. Albakri,
M. Albataineh,
W. Aldhaleei,
Robert W Aldridge,
Mulubirhan Assefa Alemayohu,
Y. Alemu,
B. Al-Fatly,
A. Al-Gheethi,
Khairat Al-Habbal,
K. Alhabib,
R. Alhassan,
Abid Ali,
Amjad Ali,
B. Ali,
Iman Ali,
Liaqat Ali,
Mohammed Usman Ali,
Rafat Ali,
Syed Shujait Shujait Ali,
Waad Ali,
G. Alicandro,
S. M. Alif,
S. Aljunid,
François Alla,
Sabah Al-Marwani,
Hesham M Al-Mekhlafi,
Sami A. Almustanyir,
Mahmoud A Alomari,
Jordi Alonso,
J. Alqahtani,
A. Alqutaibi,
Rajaa Al-Raddadi,
Ahmad Alrawashdeh,
R. al-Rifai,
S. Alrousan,
Salman Khalifah Al-Sabah,
Najim Z Alshahrani,
Zaid Altaany,
Awais Altaf,
J. Al-Tawfiq,
K. Altirkawi,
D. Aluh,
N. Alvis-Guzmán,
N. Alvis-Zakzuk,
H. Alwafi,
M. Al-Wardat,
Y. Al-Worafi,
Hany Aly,
Safwat Aly,
K. Alzoubi,
W. Al-Zyoud,
U. A. Amaechi,
Masous Aman Mohammadi,
Reza Amani,
Sohrab Amiri,
Mohammad Hosein Amirzade-Iranaq,
E. Ammirati,
Hubert Amu,
D. Amugsi,
G. Amusa,
R. Ancuceanu,
Deanna Anderlini,
Jason A Anderson,
Pedro Prata Andrade,
C. Andrei,
Tudorel Andrei,
S. Anenberg,
Dhanalakshmi Angappan,
Colin Angus,
Abhishek Anil,
Sneha Anil,
Afifa Anjum,
Amir Anoushiravani,
I. Antonazzo,
Catherine M. Antony,
E. Antriyandarti,
B. S. Anuoluwa,
Davood Anvari,
Saeid Anvari,
Saleha Anwar,
S. Anwar,
R. Anwer,
Ekenedilichukwu Emmanuel Anyabolo,
A. Anyasodor,
Geminn Louis C. Apostol,
J. Arabloo,
R. Bahri,
Mosab Arafat,
Demelash Areda,
Brhane Berhe Aregawi,
A. Aremu,
Benedetta Armocida,
Michael Benjamin Arndt,
J. Ärnlöv,
Mahwish Arooj,
A. Artamonov,
K. D. Artanti,
Idowu Aruleba,
Ashok Arumugam,
A. Asbeutah,
Saeed Asgary,
A. Asgedom,
Charlie Ashbaugh,
Mubarek Yesse Ashemo,
T. Ashraf,
Amir Askarinejad,
Michael Assmus,
Thomas Astell-Burt,
Mohammad Athar,
S. Athari,
Prince Atorkey,
A. Atreya,
A. Aujayeb,
M. Ausloos,
L. Ávila-Burgos,
Andargie Abate Awoke,
B. Quintanilla,
H. Ayatollahi,
Carlos Ayestas Portugal,
J. Ayuso-Mateos,
S. Azadnajafabad,
Rui M S Azevedo,
G. Azhar,
Hosein Azizi,
A. Azzam,
I. Backhaus,
Muhammad Badar,
A. Badiye,
Arvind Bagga,
Soroush Baghdadi,
Nasser Bagheri,
S. Bagherieh,
Pegah Bahrami Taghanaki,
Ruhai Bai,
A. Baig,
Jennifer L Baker,
S. Bakkannavar,
Madhan Balasubramanian,
Ovidiu Constantin Baltatu,
Kiran Bam,
Soham Bandyopadhyay,
B. Banik,
Palash Chandra Banik,
A. Banke-Thomas,
Hansi Bansal,
M. Barchitta,
Mainak Bardhan,
Erfan Bardideh,
S. Barker-Collo,
T. Bärnighausen,
F. Barone-Adesi,
H. Barqawi,
L. Barrero,
Amadou Barrow,
Sandra Barteit,
Z. Basharat,
A. Basiru,
João Diogo Basso,
Mohammad-Mahdi Bastan,
Sanjay Basu,
Sai Batchu,
Kavita Batra,
Ravi Batra,
B. Baune,
M. Bayati,
N. Bayileyegn,
Thomas Beaney,
A. Behnoush,
M. Beiranvand,
Yannick Béjot,
A. Bekele,
U. Belgaumi,
A. Bell,
Michelle L. Bell,
Muhammad Bashir Bello,
O. Bello,
Luis Belo,
A. Beloukas,
S. Bendak,
Derrick A. Bennett,
F. Bennitt,
I. Benseñor,
H. Benzian,
Azizullah Beran,
Zombor Berezvai,
Eduardo Bernabé,
Robert S Bernstein,
Paulo J G Bettencourt,
A. Bhagavathula,
Neeraj Bhala,
Dinesh Bhandari,
Nikha Bhardwaj,
Pankaj Bhardwaj,
Sonu M M Bhaskar,
A. N. Bhat,
Vivek Bhat,
G. K. Bhatti,
Jasvinder Singh Bhatti,
M. Bhatti,
Rajbir Bhatti,
M. Bhuiyan,
Z. Bhutta,
B. Bikbov,
J. Bishai,
C. Bisignano,
Atanu Biswas,
Bijit Biswas,
R. Biswas,
T. Bjørge,
M. K. Boachie,
Hosea Boakye,
M. Bockarie,
V. Bodolica,
Aadam Olalekan Bodunrin,
Eyob Ketema Bogale,
S. Bolla,
A. Boloor,
Milad Hashemi,
S. Boppana,
B. Basara,
Hamed Borhany,
Alejandro Botero Carvajal,
S. Bouaoud,
S. Boufous,
Rupert RA Bourne,
Christopher Boxe,
Dejana Braithwaite,
L. C. Brant,
A. Brar,
N. Breitborde,
S. Breitner,
H. Brenner,
A. Briko,
Gabrielle Britton,
Colin Stewart Brown,
A. Browne,
A. Brunoni,
Dana Bryazka,
Norma B. Bulamu,
Lemma N Bulto,
Danilo Buonsenso,
Katrin Burkart,
Richard A Burns,
Reinhard Busse,
Yasser Bustanji,
Nadeem Shafique Butt,
Z. Butt,
F. C. Santos,
Jack Cagney,
Lucero Cahuana-Hurtado,
D. Calina,
L. Cámera,
Luciana Aparecida Campos,
Ismael Campos-Nonato,
Chao Cao,
Fan Cao,
Yubin Cao,
Angelo Capodici,
Rosario Cárdenas,
Sinclair Carr,
Giulia Carreras,
J. Carrero,
A. Carugno,
F. Carvalho,
M. Carvalho,
J. Castaldelli-Maia,
C. Castañeda-Orjuela,
G. Castelpietra,
Ferrán Catalá-López,
A. Catapano,
M. Cattaruzza,
A. Caye,
Christopher R. Cederroth,
Luca Cegolon,
Muthia Cenderadewi,
Kelly M. Cercy,
Ester Cerin,
J. Chadwick,
C. Chakraborty,
P. Chakraborty,
Sandip Chakraborty,
Jeffrey Shi Kai Chan,
Raymond N C Chan,
J. Chandan,
Rama M Chandika,
Pankaj Chaturvedi,
An-Tian Chen,
Catherine S Chen,
Haowei Chen,
Meng Xuan Chen,
Mingling Chen,
Simiao Chen,
Ching-Yu Cheng,
Esther T W Cheng,
N. Cherbuin,
Gerald Chi,
Fatemeh Chichagi,
Odgerel Chimed-Ochir,
R. Chimoriya,
Patrick R. Ching,
Jesus Lorenzo Chirinos-Caceres,
Abdulaal Chitheer,
William C S Cho,
Bryan Chong,
Hitesh Chopra,
Rajiv Chowdhury,
D. Christopher,
D. Chu,
I. Chukwu,
Eric Chung,
Sheng-Chia Chung,
M. Chutiyami,
Iolanda Cioffi,
Rebecca M. Cogen,
Aaron J Cohen,
A. Columbus,
J. Conde,
A. Corlateanu,
Samuele Cortese,
P. Cortesi,
V. M. Costa,
Simona Costanzo,
M H Criqui,
Jessica A Cruz,
N. Cruz-Martins,
Garland T Culbreth,
A. G. D. Silva,
Omid Dadras,
X. Dai,
Zhaoli Dai,
Patience Unekwuojo Daikwo,
Lachlan L. Dalli,
G. Damiani,
Emanuele D'Amico,
Lucio D'Anna,
A. Darwesh,
Jai K Das,
Subasish Das,
N. Dash,
Mohsen Dashti,
C. Dávila-Cervantes,
N. Weaver,
D. Davițoiu,
Fernando De la Hoz,
A. Torre-Luque,
Diego De Leo,
Shayom Debopadhaya,
L. Degenhardt,
Cristian Del Bo',
Iván Delgado-Enciso,
J. Delgado-Saborit,
Chalachew Kassaw Demoze,
E. Denova-Gutiérrez,
N. Dervenis,
E. Dervišević,
Hardik D. Desai,
Rupak Desai,
Vinoth Gnana Chellaiyan Devanbu,
Syed Masudur Rahman Dewan,
A. Dhali,
K. Dhama,
Amol S. Dhane,
M. Dhimal,
M. Dhimal,
Sameer Dhingra,
Vishal R Dhulipala,
Raja Ram Dhungana,
D. Silva,
Daniel Diaz,
Luis Antonio Diaz,
Michael J Diaz,
Adriana Dima,
Delaney D Ding,
Monica Dinu,
Shirin Djalalinia,
Thanh Chi Do,
Thao Huynh Phuong Do,
Camila Bruneli do Prado,
Masoud Dodangeh,
Sushil Dohare,
K. Dokova,
Wanyue Dong,
Deepa Dongarwar,
Mario D'Oria,
F. Dorostkar,
E. R. Dorsey,
R. Doshi,
L. Doshmangir,
Robert Kokou Dowou,
T. Driscoll,
Ashel Chelsea Dsouza,
Haneil Larson Dsouza,
S. Dumith,
Bruce B Duncan,
A. Durães,
Senbagam Duraisamy,
A. Dushpanova,
P. A. Dzianach,
Arkadiusz Marian Dziedzic,
Alireza Ebrahimi,
C. Echieh,
Abdelaziz Ed-Dra,
H. Edinur,
D. Edvardsson,
Kristina Edvardsson,
Ferry Efendi,
Aziz Eftekharimehrabad,
E. Eini,
Michael Ekholuenetale,
T. Ekundayo,
Rabie Adel El Arab,
M. Zaki,
F. El-dahiyat,
N. Elemam,
F. Elgar,
Ghada ElGohary,
H. Elhabashy,
Muhammed Elhadi,
A. Elmehrath,
Omar Abdelsadek Abdou Elmeligy,
M. Elshaer,
Ibrahim Elsohaby,
T. Emeto,
Negin Esfandiari,
B. Eshrati,
Majid Eslami,
Sayed Vahid Esmaeili,
Kara Estep,
Farshid Etaee,
N. Fabin,
A. Fagbamigbe,
O. Fagbule,
S. Fahimi,
L. Falzone,
M. Fareed,
C. Farinha,
M. Faris,
P. Faris,
Andre Faro,
F. Fasina,
A. Fatehizadeh,
N. Fauk,
Timur Fazylov,
Valery L. Feigin,
Xiaoqi Feng,
S. Fereshtehnejad,
A. Feroze,
Pietro Ferrara,
A. Ferrari,
Nuno Ferreira,
G. Fetensa,
Bikila Regassa Feyisa,
I. Filip,
Florian Fischer,
Ida Fitriana,
Joanne Flavel,
Carsten Flohr,
David Flood,
L. Flor,
N. Foigt,
M. Foláyan,
Lisa M. Force,
Daniela Fortuna,
Matteo Foschi,
R. C. Franklin,
Alberto Freitas,
S. Friedman,
B. Fux,
G. Sridevi,
Péter Gaál,
Santosh Gaihre,
Márió Gajdács,
Yaseen Galali,
Silvano Gallus,
A. Gandhi,
B. Ganesan,
Mohammad Arfat Ganiyani,
Vanessa Garcia,
William M Gardner,
Ravindra K. Garg,
R. Gautam,
Tilaye Gebru Gebi,
M. W. Gebregergis,
Mesfin Gebrehiwot,
T. B. Gebremariam,
T. G. Gebremeskel,
Urge Gerema,
Lemma Getacher,
Genanew Kassie Getahun,
Molla Getie,
F. Ghadirian,
Sadegh Ghafarian,
Amir Ghaffari Jolfayi,
K. Ghailan,
A. Ghajar,
Mohammad-Reza Ghasemi,
Ghazal Ghasempour Dabaghi,
Afsaneh Ghasemzadeh,
Fariba Ghassemi,
R. Ghazy,
Ali Gholami,
Ali Gholamrezanezhad,
Nasim Gholizadeh,
Mahsa Ghorbani,
Artyom Urievich Gil,
G. Gil,
Nora M. Gilbertson,
P. Gill,
Tiffany K. Gill,
Ebisa Zerihun Gindaba,
Alem Girmay,
James C. Glasbey,
E. Gnedovskaya,
Laszlo Göbölös,
Myron Anthony Godinho,
Amit Goel,
Mahaveer Golechha,
Pouya Goleij,
Davide Golinelli,
Nelson G. M. Gomes,
S. Gopalani,
G. Gorini,
H. Goudarzi,
A. Goulart,
Mahdi Gouravani,
Anmol Goyal,
Simon Matthew Graham,
Michale Grivna,
Giuseppe Grosso,
Shi-Yang Guan,
Giovanni Guarducci,
M. I. Gubari,
Avirup Guha,
Stefano Guicciardi,
Snigdha Gulati,
David Gulisashvili,
D. Gunawardane,
Cui Guo,
A. Gupta,
Bhawna Gupta,
Mohak Gupta,
Rahul Gupta,
R. Gupta,
R. Gupta,
Sapna Gupta,
Veera Gupta,
Vijai Kumar Gupta,
V. Gupta,
Farrokh Habibzadeh,
Parham Habibzadeh,
Tesfahun Simon Hadaro,
Zahra Hadian,
Nils Haep,
Hamed Haghi-Aminjan,
D. Haghmorad,
Hailey Hagins,
D. Haile,
A. Hailu,
Adel Hajj Ali,
E. Halboub,
Aram Halimi,
Brian J. Hall,
Sebastian Haller,
R. Halwani,
R. Hamadeh,
Nadia M. Hamdy,
Sajid Hameed,
S. Hamidi,
Ahmad Hammoud,
Asif Hanif,
N. Hanifi,
Z. Haq,
Md Rabiul Haque,
H. Harapan,
Arief Hargono,
J. Haro,
Ahmed I Hasaballah,
Ikramul Hasan,
Mohammad Jahid Hasan,
S. M. M. Hasan,
H. Hasani,
M. Hasanian,
Nadim Hashmeh,
Md. Saquib Hasnain,
Amr Hassan,
I. Hassan,
Mahgol Sadat Hassan Zadeh Tabatabaei,
S. Hassani,
S. Hassanipour,
H. Hassankhani,
Johannes Haubold,
Rasmus J Havmoeller,
Simon I. Hay,
Jeffrey J. Hebert,
Omar E. Hegazi,
Tadele Yohannes Hegena,
G. Heidari,
Mohammad Heidari,
B. Helfer,
Mehdi Hemmati,
Claire A. Henson,
Molly E Herbert,
C. Herteliu,
A. Heuer,
Kamal Hezam,
T. Hinneh,
Y. Hiraike,
Nguyen Quoc Hoan,
Ramesh Holla,
Julia Hon,
Mohammad Enamul Hoque,
Nobuyuki Horita,
S. Hossain,
Seyed Ehsan Hosseini,
Hassan Hosseinzadeh,
M. Hosseinzadeh,
M. Hostiuc,
S. Hostiuc,
H. Hoven,
Mohamed Hsairi,
Johnathan M Hsu,
Chengxi Hu,
Junjie. Huang,
Md. Nazmul Huda,
E. Hulland,
M. Hultström,
K. Hushmandi,
Javid Hussain,
N. Hussein,
Chantal K Huynh,
H. Huynh,
S. E. Ibitoye,
O. O. Idowu,
Audrey L Ihler,
Nayu Ikeda,
K. Ikuta,
O S Ilesanmi,
Irena M. Ilic,
Milena D. Ilic,
M. Imam,
Mustapha Immurana,
L. Inbaraj,
L. Irham,
M. A. Isa,
Md. Rabiul Islam,
Faisal Ismail,
N. Ismail,
Hiroyasu Iso,
Gaetano Isola,
Masao Iwagami,
C. C. Iwu,
C. Iwu-Jaja,
J. Vinothini,
J. Jaafari,
Louis Jacob,
K. Jacobsen,
F. Jadidi‐Niaragh,
Kasra Jahankhani,
N. Jahanmehr,
H. Jahrami,
Akhil Jain,
Nityanand Jain,
A. Jairoun,
Abhishek Jaiswal,
Mihajlo Jakovljevic,
R. J. Yengejeh,
R. Jamora,
A. Jatau,
Sabzali R. Javadov,
T. Javaheri,
S. Jayaram,
Jayakumar Jeganathan,
B. Jeswani,
Heng Jiang,
C. Johnson,
Mohammad Jokar,
N. Jomehzadeh,
J. Jonas,
Tamás Joó,
Abel Joseph,
Nitin Joseph,
Vivek Joshi,
Charity Ehimwenma Joshua,
J. Jozwiak,
Mikk Jürisson,
B. Kaambwa,
Alia Kabir,
Zubair Kabir,
Vidya Kadashetti,
Ethan Kahn,
Rizwan Kalani,
Feroze Kaliyadan,
Sanjay Kalra,
Rajesh Kamath,
T. Kanagasabai,
T. Kanchan,
Himal Kandel,
E. Kanmiki,
K. Kanmodi,
S. K. Kansal,
Daniel John Kapner,
Neeti Kapoor,
E. Karagiannidis,
Mehrdad Karajizadeh,
Paschalis Karakasis,
S. Karanth,
I. Karaye,
André Karch,
Asima Karim,
Hanie Karimi,
Shilpi Karmakar,
F. Kashoo,
Hengameh Kasraei,
Woldeteklehaymanot Kassahun,
N. Kassebaum,
Molly B Kassel,
S. Katikireddi,
J. Kauppila,
Norito Kawakami,
N. Kaydi,
G. Kayode,
Foad Kazemi,
P. Keiyoro,
L. Kemmer,
John H. Kempen,
Jessica A Kerr,
E. Kesse‐Guyot,
Yousef S. Khader,
M. Khafaie,
H. Khajuria,
A. Khalaji,
Mariam Khalil,
Alireza Khalilian,
F. Khamesipour,
Asaduzzaman Khan,
M. N. Khan,
Maseer Khan,
Mohammad Jobair Khan,
Moien A. B. Khan,
S. Khanmohammadi,
K. Khatab,
Haitham Khatatbeh,
M. Khatatbeh,
M. Khatib,
Armin Khavandegar,
Hamid Reza Khayat Kashani,
F. F. Khidri,
Elaheh Khodadoust,
Moein Khormali,
Zahra Khorrami,
A. Khosla,
Mahmood Khosrowjerdi,
H. Khreis,
Helda Khusun,
Zemene Demelash Kifle,
Kwanghyun Kim,
Min Seo Kim,
Y. Kim,
R. Kimokoti,
A. Kisa,
S. Kisa,
Luke D. Knibbs,
Ann Kristin Skrindo Knudsen,
David S Q Koh,
Ali-Asghar Kolahi,
Farzad Kompani,
Jianqiu Kong,
Gerbrand Koren,
M. Korja,
V. A. Korshunov,
O. Korzh,
S. Kosen,
Nikhil Kothari,
Parvaiz A. Koul,
S. Laxminarayana,
K. Krishan,
V. Krishnamoorthy,
Yuvaraj Krishnamoorthy,
Bindu Krishnan,
Kristopher J. Krohn,
B. K. Defo,
B. K. Bicer,
Md Abdul Kuddus,
M. Kuddus,
Nuworza Kugbey,
I. Kuitunen,
M. Kulimbet,
Vishnutheertha Kulkarni,
Ashish Kumar,
Nithin Kumar,
Vijay Kumar,
Satyajit Kundu,
O. Kurmi,
Asep Kusnali,
Dian Kusuma,
T. Kutluk,
C. L. Vecchia,
M. Ladan,
Lucie Laflamme,
Chandrakant Lahariya,
D. Lai,
D. Lal,
T. Lallukka,
Judit Lám,
Q. Lan,
Tuo Lan,
I. Landires,
Francesco Lanfranchi,
Berthold Langguth,
V. Lansingh,
Ariane Laplante-Lévesque,
Bagher Larijani,
Anders O Larsson,
Savita Lasrado,
P. Lauriola,
Huu-Hoai Le,
Long Khanh Dao Le,
Nhi Huu Hanh Le,
Thao Thi Thu Le,
J. Leasher,
C. Ledda,
Munjae Lee,
P. H. Lee,
S. Lee,
Shaun Wen Huey Lee,
Yo Han Lee,
K. E. LeGrand,
J. Leigh,
E. Leong,
T. L. Lerango,
H. Lescinsky,
Janni Leung,
Ming-Chieh Li,
Wang-Zhong Li,
Wei Li,
Yichong Li,
Zhihui Li,
V. Ligade,
Lee-Ling Lim,
Stephen S. Lim,
R. Lin,
Shuzhi Lin,
Chaojie Liu,
Gang Liu,
Jinli Liu,
Jue Liu,
Richard T Liu,
Shiwei Liu,
Wei Liu,
Xiaofeng Liu,
Xuefeng Liu,
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E. Gakidou
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