|
🐜
|
Development of a human genetics-guided priority score for 19,365 genes and 399 drug indications
17 auth.
Á. Duffy,
B. Petrazzini,
David Stein,
Joshua K. Park,
I. Forrest,
Kyle Gibson,
H. M. Vy,
Robert Chen,
C. Márquez-Luna,
M. Mort,
...
M. Verbanck,
A. Schlessinger,
Y. Itan,
David N Cooper,
G. Rocheleau,
Daniel M. Jordan,
Ron Do
|
3 |
2024 |
3
🐜
|
|
🐜
|
Individuals with JAK1 variants are affected by syndromic features encompassing autoimmunity, atopy, colitis, and dermatitis
39 auth.
Michael E Horesh,
Marta Martin-Fernandez,
C. Gruber,
S. Buta,
Tom Le Voyer,
Eve Puzenat,
Harry Lesmana,
Yiming Wu,
Ashley Richardson,
David Stein,
Stephanie Hodeib,
Mariam Youssef,
Jacob A Kurowski,
Elizabeth Feuille,
Luis A Pedroza,
...
R. Fuleihan,
Alexandria Haseley,
Alain Hovnanian,
P. Quartier,
J. Rosain,
Georgina Davis,
Daniel Mullan,
O. Stewart,
Rosheel Patel,
Angelica E Lee,
Rebecca Rubinstein,
Leyla Ewald,
Nikhil Maheshwari,
Virginia Rahming,
Ivan K. Chinn,
J. Lupski,
Jordan S. Orange,
V. Sancho-Shimizu,
J. Casanova,
N. Abul-Husn,
Y. Itan,
Joshua D. Milner,
J. Bustamante,
D. Bogunovic
|
3 |
2024 |
3
🐜
|
|
🐬
|
Exploring the Druggable Conformational Space of Protein Kinases Using AI-Generated Structures
Noah B. Herrington,
David Stein,
Yan Chak Li,
Gaurav Pandey,
A. Schlessinger
|
2 |
2023 |
2
🐬
|
|
🐜
|
Expanding drug targets for 112 chronic diseases using a machine learning-assisted genetic priority score
13 auth.
Robert Chen,
Á. Duffy,
B. Petrazzini,
H. M. Vy,
David Stein,
M. Mort,
Joshua K. Park,
A. Schlessinger,
Y. Itan,
David N Cooper,
...
Daniel M. Jordan,
G. Rocheleau,
Ron Do
|
0 |
2024 |
0
🐜
|
