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A Review on Mechanisms of Anti Tumor Activity of Chalcones.
13 auth.
Rahul Sharma,
Rakesh Kumar,
Rishi Kodwani,
S. Kapoor,
Anukriti Khare,
Ritu Bansal,
Sonali Khurana,
Sandhya Singh,
Jennifer C. Thomas,
B. Roy,
...
Rajendra Phartyal,
Shukla Saluja,
Sanjay Kumar
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5 |
2015 |
5
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Identification of the Clinical Candidate (R)-(1-(4-Fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone (CORT125134): A Selective Glucocorticoid Receptor (GR) Antagonist.
10 auth.
H. Hunt,
J. Belanoff,
I. Walters,
B. Gourdet,
Jennifer C. Thomas,
Naomi Barton,
...
J. Unitt,
T. Phillips,
D. Swift,
Emily Eaton
|
5 |
2017 |
5
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Preclinical Characterization of PC786, an Inhaled Small-Molecule Respiratory Syncytial Virus L Protein Polymerase Inhibitor
21 auth.
M. Coates,
Daniel W. Brookes,
Young-In Kim,
Heather E. Allen,
Euan A. F. Fordyce,
E. Meals,
Thomas Colley,
Claire-Lise Ciana,
Guillaume F Parra,
V. Sherbukhin,
...
J. Stockwell,
Jennifer C. Thomas,
S. Hunt,
Lauren Anderson-Dring,
S. Onions,
L. Cass,
P. Murray,
Kazuhiro Ito,
P. Strong,
J. DeVincenzo,
Garth William Rapeport
|
5 |
2017 |
5
🐜
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🐜
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1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile.
9 auth.
H. Hunt,
J. Belanoff,
E. Golding,
B. Gourdet,
T. Phillips,
D. Swift,
...
Jennifer C. Thomas,
J. Unitt,
I. Walters
|
4 |
2015 |
4
🐜
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|
🐜
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Discovery of novel benzothienoazepine derivatives as potent inhibitors of respiratory syncytial virus.
15 auth.
Euan A. F. Fordyce,
Daniel W. Brookes,
Claire Lise-Ciana,
M. Coates,
S. Hunt,
Kazuhiro Ito,
J. King-Underwood,
S. Onions,
Guillaume F Parra,
Garth William Rapeport,
...
V. Sherbukhin,
J. Stockwell,
P. Strong,
Jennifer C. Thomas,
John Murray
|
4 |
2017 |
4
🐜
|
|
🐜
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Discovery and Optimization of Potent and Orally Available CTP Synthetase Inhibitors for Use in Treatment of Diseases Driven by Aberrant Immune Cell Proliferation.
24 auth.
Andrew Novak,
D. Laughton,
R. Lane,
Emma E. Blackham,
Jennifer C. Thomas,
E. Chatzopoulou,
Joe W Wrigglesworth,
Abdul Quddus,
Samatar Ahmed,
David Cousin,
...
Lorna A. Duffy,
Nathalie Dubois,
J. Unitt,
Katalin Orban,
Edward Browne,
M. Ward,
David K. Mycock,
M. Ieva,
N. Bland,
P. George,
T. Bourne,
H. Asnagli,
L. Birch,
Geraint Jones
|
1 |
2022 |
1
🐜
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Preclinical characterization of the inhaled small molecule respiratory syncytial virus L-1 protein polymerase inhibitor , PC 786 2 3 4
22 auth.
M. Coates,
Daniel W. Brookes,
Young-In Kim,
Heather E. Allen,
Euan A. F. Fordyce,
E. Meals,
Thomas Colley,
Claire-Lise Ciana,
Guillaume F Parra,
Vladimír,
...
Sherbukhin,
J. Stockwell,
Jennifer C. Thomas,
S. Hunt,
Lauren,
Anderson-Dring,
S. Onions,
L. Cass,
P. Murray,
Kazuhiro Ito,
J. DeVincenzo,
Garth William Rapeport
|
1 |
2017 |
1
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