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🐜
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Durable Remissions with Ivosidenib in IDH1‐Mutated Relapsed or Refractory AML
40 auth.
C. Dinardo,
E. Stein,
S. de Botton,
G. Roboz,
J. Altman,
A. Mims,
R. Swords,
R. Collins,
G. Mannis,
D. Pollyea,
W. Donnellan,
A. Fathi,
A. Pigneux,
H. Erba,
G. Prince,
...
A. Stein,
G. Uy,
J. Foran,
E. Traer,
R. Stuart,
M. Arellano,
J. Slack,
M. Sekeres,
C. Willekens,
S. Choe,
Hongfang Wang,
V. Zhang,
K. Yen,
S. Kapsalis,
Hua Yang,
D. Dai,
Bin Fan,
M. Goldwasser,
Hua Liu,
S. Agresta,
Bin Wu,
E. Attar,
M. Tallman,
R. Stone,
H. Kantarjian
|
10 |
2018 |
10
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An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia
27 auth.
B. Knoechel,
J. Roderick,
Kaylyn E. Williamson,
Jiang Zhu,
Jens G. Lohr,
M. J. Cotton,
Shawn M. Gillespie,
D. Fernández,
Manching Ku,
Hongfang Wang,
F. Piccioni,
S. Silver,
M. Jain,
Daniel S Pearson,
Michael J. Kluk,
...
Christopher J. Ott,
L. Shultz,
M. Brehm,
D. Greiner,
A. Gutierrez,
K. Stegmaier,
A. Kung,
D. Root,
J. Bradner,
J. Aster,
M. Kelliher,
B. Bernstein
|
8 |
2014 |
8
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|
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Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.
31 auth.
G. Roboz,
C. Dinardo,
E. Stein,
S. de Botton,
A. Mims,
G. Prince,
J. Altman,
M. Arellano,
W. Donnellan,
H. Erba,
G. Mannis,
D. Pollyea,
A. Stein,
G. Uy,
J. Watts,
...
A. Fathi,
H. Kantarjian,
M. Tallman,
S. Choe,
D. Dai,
Bin Fan,
Hongfang Wang,
V. Zhang,
K. Yen,
S. Kapsalis,
D. Hickman,
Hua Liu,
S. Agresta,
Bin Wu,
E. Attar,
R. Stone
|
8 |
2019 |
8
🐜
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|
🦁
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Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells
13 auth.
Hongfang Wang,
James Y. Zou,
Bo Zhao,
E. Johannsen,
T. Ashworth,
Hoifung Wong,
W. Pear,
J. Schug,
S. Blacklow,
K. Arnett,
...
B. Bernstein,
E. Kieff,
J. Aster
|
7 |
2011 |
7
🦁
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|
🦁
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NOTCH1–RBPJ complexes drive target gene expression through dynamic interactions with superenhancers
10 auth.
Hongfang Wang,
C. Zang,
Len Taing,
K. Arnett,
Y. J. Wong,
W. Pear,
...
S. Blacklow,
X. Liu,
J. Aster,
Richard A. Flavell
|
7 |
2013 |
7
🦁
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|
🐜
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Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth
13 auth.
Bo Zhao,
James Y. Zou,
Hongfang Wang,
E. Johannsen,
Chih-wen Peng,
John Quackenbush,
J. Mar,
C. Morton,
M. Freedman,
S. Blacklow,
...
J. Aster,
B. Bernstein,
E. Kieff
|
7 |
2011 |
7
🐜
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|
🐜
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T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling
11 auth.
Kristine Germar,
Marei Dose,
Tassos Konstantinou,
Jiangwen Zhang,
Hongfang Wang,
Camille Lobry,
...
K. Arnett,
S. Blacklow,
I. Aifantis,
J. Aster,
F. Gounari
|
7 |
2011 |
7
🐜
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|
🐜
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Characterization of Notch1 Antibodies That Inhibit Signaling of Both Normal and Mutated Notch1 Receptors
30 auth.
M. Aste‐Amezaga,
Ningyan Zhang,
J. Lineberger,
B. A. Arnold,
T. Toner,
Mingcheng Gu,
Lingyi Huang,
Salvatore Vitelli,
Kim T Vo,
Peter Haytko,
J. Zhao,
F. Baleydier,
Sarah L'heureux,
Hongfang Wang,
W. Gordon,
...
Elizabeth A Thoryk,
M. B. Andrawes,
K. Tiyanont,
K. Stegmaier,
G. Roti,
K. Ross,
Laura L. Franlin,
Hui Wang,
Fubao Wang,
M. Chastain,
A. Bett,
L. Audoly,
J. Aster,
S. Blacklow,
H. Huber
|
7 |
2010 |
7
🐜
|
|
🐜
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Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study.
31 auth.
E. Stein,
C. Dinardo,
A. Fathi,
A. Mims,
K. Pratz,
M. Savona,
A. Stein,
R. Stone,
E. Winer,
C. Seet,
H. Döhner,
D. Pollyea,
J. Mccloskey,
O. Odenike,
B. Löwenberg,
...
G. Ossenkoppele,
P. Patel,
M. Roshal,
M. Frattini,
F. Lersch,
A. Franovic,
S. Nabhan,
Bin Fan,
S. Choe,
Hongfang Wang,
Bin Wu,
L. Hua,
Caroline Almon,
Michael Cooper,
H. Kantarjian,
M. Tallman
|
7 |
2020 |
7
🐜
|
|
🐜
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High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling
15 auth.
H. Medyouf,
Samuel Gusscott,
Hongfang Wang,
Jen-Chieh Tseng,
C. Wai,
Oksana Nemirovsky,
A. Trumpp,
F. Pflumio,
J. Carboni,
M. Gottardis,
...
M. Pollak,
A. Kung,
J. Aster,
M. Holzenberger,
A. Weng
|
7 |
2011 |
7
🐜
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|
🐜
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Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia
20 auth.
Yumi Yashiro‐Ohtani,
Hongfang Wang,
C. Zang,
K. Arnett,
Will Bailis,
Y. Ho,
B. Knoechel,
Claudia B. Lanauze,
Lumena Louis,
Katherine S. Forsyth,
...
Sujun Chen,
Y. Chung,
J. Schug,
G. Blobel,
S. Liebhaber,
B. Bernstein,
S. Blacklow,
Xiaole Shirley Liu,
J. Aster,
W. Pear
|
7 |
2014 |
7
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