π
|
Histone H3K27ac separates active from poised enhancers and predicts developmental state
13 auth.
M. Creyghton,
A. Cheng,
G. Welstead,
T. Kooistra,
B. Carey,
Eveline J. Steine,
J. Hanna,
Michael A. Lodato,
G. Frampton,
P. Sharp,
...
L. Boyer,
R. Young,
R. Jaenisch
|
11 |
2010 |
11 π
|
π¬
|
RNAi Double-Stranded RNA Directs the ATP-Dependent Cleavage of mRNA at 21 to 23 Nucleotide Intervals
P. Zamore,
T. Tuschl,
P. Sharp,
D. Bartel
|
11 |
2000 |
11 π¬
|
π
|
In vivo genome editing using Staphylococcus aureus Cas9
13 auth.
F. Ran,
Le Cong,
Winston X. Yan,
David A. Scott,
J. Gootenberg,
Andrea J. Kriz,
Bernd Zetsche,
Ophir Shalem,
Xuebing Wu,
K. Makarova,
...
E. Koonin,
P. Sharp,
Feng Zhang
|
11 |
2015 |
11 π
|
π’
|
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
Margaret S. Ebert,
J. Neilson,
P. Sharp
|
11 |
2007 |
11 π’
|
π’
|
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids
A. Berk,
P. Sharp
|
11 |
1977 |
11 π’
|
π
|
Coactivator condensation at super-enhancers links phase separation and gene control
23 auth.
Benjamin R. Sabari,
Alessandra DallβAgnese,
Ann Boija,
Isaac A. Klein,
Eliot L. Coffey,
Krishna Shrinivas,
B. Abraham,
N. Hannett,
A. V. Zamudio,
John C. Manteiga,
...
Charles H. Li,
Y. Guo,
Daniel S. Day,
Jurian Schuijers,
E. Vasile,
S. Malik,
Denes Hnisz,
Tong Ihn Lee,
I. CissΓ©,
R. Roeder,
P. Sharp,
A. Chakraborty,
R. Young
|
10 |
2018 |
10 π
|
π’
|
Specificity of microRNA target selection in translational repression.
John G Doench,
P. Sharp
|
10 |
2004 |
10 π’
|
π
|
CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
21 auth.
Randall J. Platt,
Sidi Chen,
Yang Zhou,
Michael J. Yim,
L. Swiech,
Hannah R. Kempton,
J. Dahlman,
Oren Parnas,
T. Eisenhaure,
M. JovanoviΔ,
...
D. Graham,
S. Jhunjhunwala,
Matthias Heidenreich,
R. Xavier,
R. Langer,
Daniel G. Anderson,
N. Hacohen,
A. Regev,
G. Feng,
P. Sharp,
Feng Zhang
|
10 |
2014 |
10 π
|
π
|
Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17βΌ92 Family of miRNA Clusters
13 auth.
A. Ventura,
Amanda G. Young,
M. Winslow,
L. Lintault,
A. Meissner,
S. Erkeland,
J. Newman,
R. Bronson,
D. Crowley,
J. Stone,
...
R. Jaenisch,
P. Sharp,
T. Jacks
|
10 |
2008 |
10 π
|
π’
|
Roles for MicroRNAs in Conferring Robustness to Biological Processes
Margaret S. Ebert,
P. Sharp
|
10 |
2012 |
10 π’
|
π’
|
Gene silencing in mammals by small interfering RNAs
Michael T. McManus,
P. Sharp
|
10 |
2002 |
10 π’
|
π
|
Lentivirus-delivered stable gene silencing by RNAi in primary cells.
12 auth.
S. Stewart,
D. Dykxhoorn,
D. Palliser,
H. Mizuno,
E. Yu,
D. An,
...
D. Sabatini,
I. Chen,
W. Hahn,
P. Sharp,
R. Weinberg,
C. Novina
|
10 |
2003 |
10 π
|
π
|
Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells
20 auth.
A. Marson,
S. Levine,
Megan F. Cole,
G. Frampton,
T. Brambrink,
Sarah E. Johnstone,
M. Guenther,
W. K. Johnston,
Marius Wernig,
J. Newman,
...
J. M. Calabrese,
Lucas M. Dennis,
T. Volkert,
Sumeet Gupta,
Jennifer M. Love,
N. Hannett,
P. Sharp,
D. Bartel,
R. Jaenisch,
R. Young
|
10 |
2008 |
10 π
|
π¬
|
Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites
R. Sandberg,
J. Neilson,
Arup Sarma,
P. Sharp,
C. Burge
|
10 |
2008 |
10 π¬
|