|
🐜
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A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation.
10 auth.
Ryan P. Wurz,
Ken Dellamaggiore,
Hannah Dou,
Noelle Javier,
M. Lo,
J. McCarter,
...
D. Mohl,
Christine Sastri,
J. Lipford,
V. Cee
|
7 |
2017 |
7
🐜
|
|
🐜
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Characterization of a Novel FLT3 BiTE Molecule for the Treatment of Acute Myeloid Leukemia
26 auth.
B. Brauchle,
R. Goldstein,
Christine M. Karbowski,
A. Henn,
Chi-Ming Li,
V. Bücklein,
Christina Krupka,
M. Boyle,
Priya Koppikar,
Sascha Haubner,
J. Wahl,
Christoph Dahlhoff,
Tobias Raum,
Matthew J. Rardin,
Christine Sastri,
...
D. Rock,
M. von Bergwelt-Baildon,
Brendon T. Frank,
K. Metzeler,
Ryan Case,
M. Friedrich,
M. Balazs,
K. Spiekermann,
A. Coxon,
M. Subklewe,
T. Arvedson
|
5 |
2020 |
5
🐜
|
|
🐜
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Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors.
16 auth.
Bin Wu,
Hui-Ling Wang,
V. Cee,
B. Lanman,
Thomas E. Nixey,
L. Pettus,
Anthony B. Reed,
Ryan P Wurz,
Nadia Guerrero,
Christine Sastri,
...
J. Winston,
J. Lipford,
Matthew R. Lee,
C. Mohr,
K. Andrews,
A. Tasker
|
4 |
2015 |
4
🐜
|
|
🐜
|
Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors.
33 auth.
L. Pettus,
K. Andrews,
S. Booker,
Jie Chen,
V. Cee,
F. Chavez,
Yuping Chen,
Heather Eastwood,
Nadia Guerrero,
B. Herberich,
D. Hickman,
B. Lanman,
Jimmy Laszlo,
Matthew R. Lee,
J. Lipford,
...
Bethany Mattson,
C. Mohr,
Y. Nguyen,
M. H. Norman,
D. Powers,
Anthony B. Reed,
K. Rex,
Christine Sastri,
N. Tamayo,
Paul Wang,
J. Winston,
Bin Wu,
Tian Wu,
Ryan P. Wurz,
Yang Xu,
Yihong Zhou,
A. Tasker,
Hui-Ling Wang
|
4 |
2016 |
4
🐜
|
|
🐜
|
The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors.
17 auth.
Hui-Ling Wang,
V. Cee,
F. Chavez,
B. Lanman,
Anthony B. Reed,
Bin Wu,
Nadia Guerrero,
J. Lipford,
Christine Sastri,
J. Winston,
...
K. Andrews,
Xin Huang,
Matthew R. Lee,
C. Mohr,
Yang Xu,
Yihong Zhou,
A. Tasker
|
4 |
2015 |
4
🐜
|
|
🐜
|
The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors.
25 auth.
Ryan P Wurz,
L. Pettus,
Claire L M Jackson,
Bin Wu,
Hui-Ling Wang,
B. Herberich,
V. Cee,
B. Lanman,
Anthony B. Reed,
F. Chavez,
Thomas E. Nixey,
Jimmy Laszlo,
Paul Wang,
Y. Nguyen,
Christine Sastri,
...
Nadia Guerrero,
J. Winston,
J. Lipford,
Matthew R. Lee,
K. Andrews,
C. Mohr,
Yang Xu,
Yihong Zhou,
Darren L. Reid,
Andrew Tasker
|
4 |
2015 |
4
🐜
|
|
🐜
|
Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors.
28 auth.
V. Cee,
F. Chavez,
B. Herberich,
B. Lanman,
L. Pettus,
Anthony B. Reed,
Bin Wu,
Ryan P. Wurz,
K. Andrews,
Jie Chen,
D. Hickman,
Jimmy Laszlo,
Matthew R. Lee,
Nadia Guerrero,
Bethany Mattson,
...
Y. Nguyen,
C. Mohr,
K. Rex,
Christine Sastri,
Paul Wang,
Qiong Wu,
Tian Wu,
Yang Xu,
Yihong Zhou,
J. Winston,
J. Lipford,
A. Tasker,
Hui-Ling Wang
|
4 |
2016 |
4
🐜
|
|
🐜
|
Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors.
23 auth.
Ryan P. Wurz,
Christine Sastri,
D. D'amico,
B. Herberich,
Claire L M Jackson,
L. Pettus,
A. Tasker,
Bin Wu,
Nadia Guerrero,
J. Lipford,
...
J. Winston,
Yajing Yang,
Paul Wang,
Y. Nguyen,
K. Andrews,
Xin Huang,
Matthew R. Lee,
C. Mohr,
J. D. Zhang,
D. Reid,
Yang Xu,
Yihong Zhou,
Hui-Ling Wang
|
4 |
2016 |
4
🐜
|
