J. Baird's Profile

Role	Title	Level	Year	L/R
🐜	Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer. 24 auth. G. Tria, T. Abrams, J. Baird, H. Burks, B. Firestone, L. Gaither, L. Hamann, Guo He, C. Kirby, Sunkyu Kim, ... F. Lombardo, Kaitlin J Macchi, D. McDonnell, Y. Mishina, J. Norris, Jill Nunez, C. Springer, Yingchuan Sun, Noel M. Thomsen, Chunrong Wang, Jianling Wang, Bing Yu, Choi-Lai Tiong-Yip, S. Peukert	6	2018	6 🐜
🐜	ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor 24 auth. Z. Mounir, Joshua M. Korn, T. Westerling, Fallon Lin, C. Kirby, M. Schirle, Gregory McAllister, G. Hoffman, N. Ramadan, A. Hartung, ... Yan Feng, D. R. Kipp, C. Quinn, M. Fodor, J. Baird, Marie Schoumacher, R. Meyer, J. Deeds, Gilles Buchwalter, T. Stams, N. Keen, W. Sellers, Myles A. Brown, R. Pagliarini	5	2016	5 🐜
🐜	The novolactone natural product disrupts the allosteric regulation of Hsp70. 24 auth. A. Quamrul Hassan, Christina A. Kirby, Wenlai Zhou, Tim Schuhmann, Roman Kityk, D. R. Kipp, J. Baird, Jinyun Chen, Yaoyu Chen, Franklin Chung, ... D. Hoepfner, N. Movva, R. Pagliarini, F. Petersen, C. Quinn, D. Quinn, R. Riedl, Esther K. Schmitt, Anne Schitter, T. Stams, Christian Studer, Pascal D. Fortin, Matthias P. Mayer, H. Sadlish	5	2015	5 🐜
🐜	Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERα+ Breast Cancer. 21 auth. H. Burks, T. Abrams, C. Kirby, J. Baird, Alex Fekete, L. Hamann, Sunkyu Kim, F. Lombardo, Alice T. Loo, Danuta Lubicka, ... Kaitlin J Macchi, D. McDonnell, Y. Mishina, J. Norris, Jill Nunez, Chitra Saran, Yingchuan Sun, Noel M. Thomsen, Chunrong Wang, Jianling Wang, S. Peukert	4	2017	4 🐜
🐬	Docking to Erlotinib Off-Targets Leads to Inhibitors of Lung Cancer Cell Proliferation with Suitable in Vitro Pharmacokinetics Liwei Li, Jing Li, M. Khanna, Inha Jo, J. Baird, S. Meroueh	4	2010	4 🐬
🐜	Clearance of plasma PCSK9 via the asialoglycoprotein receptor mediated by heterobifunctional ligands. 18 auth. J. Bagdanoff, Thomas M Smith, M. Allan, P. O'Donnell, Zachary Nguyen, Elizabeth A Moore, J. Baird, Shuangxi Wang, V. Subramanian, B. Tigani, ... D. Nettleton, L. Monovich, I. Lewis, Alec N Flyer, B. Granda, J. Blankenship, D. Barnes‐Seeman, K. B. Clairmont	3	2023	3 🐜
🐬	Docking Small Molecules to Predicted Off-Targets of the Cancer Drug Erlotinib Leads to Inhibitors of Lung Cancer Cell Proliferation with Suitable In vitro Pharmacokinetic Properties. Liwei Li, Jing Li, M. Khanna, Inha Jo, J. Baird, S. Meroueh	2	2010	2 🐬
🐢	ESTROGEN RECEPTOR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH LSZ102 C. Kirby, J. Baird	0	2018	0 🐢