|
π
|
Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial
153 auth.
K. Shitara,
M. ΓzgΓΌroΔlu,
Y. Bang,
M. Di Bartolomeo,
M. MandalΓ ,
M. Ryu,
L. Fornaro,
T. OlesiΕski,
C. Caglevic,
H. Chung,
K. Muro,
E. Goekkurt,
W. Mansoor,
R. McDermott,
E. Shacham-Shmueli,
...
Xinqun Chen,
C. Mayo,
S. Kang,
A. Ohtsu,
C. Fuchs,
G. Lerzo,
J. O'Connor,
G. Mendez,
J. Lynam,
N. Tebbutt,
M. Wong,
A. Strickland,
C. Karapetis,
D. Goldstein,
P. Vasey,
J. Van Laethem,
E. Van Cutsem,
S. Berry,
M. Vincent,
Bettina Muller,
F. Rey,
A. Zambrano,
J. Guerra,
M. Krogh,
L. Baeksgaard,
M. Yilmaz,
A. Elme,
Andrus Magi,
P. Auvinen,
T. Alanko,
M. Moehler,
V. Kunzmann,
T. Seufferlein,
P. Thuss-Patience,
T. Hoehler,
G. Haag,
S. Al-Batran,
H. Castro,
K. Lopez,
Mynor Aguilar Vasquez,
Mario Sandoval,
K. Lam,
S. Cuffe,
C. Kelly,
R. Geva,
A. Hubert,
A. Beny,
B. Brenner,
Aprile Giuseppe,
A. Falcone,
E. Maiello,
R. Passalacqua,
V. Montesarchio,
H. Hara,
K. Chin,
T. Nishina,
Y. Komatsu,
N. Machida,
S. Hironaka,
T. Satoh,
T. Tamura,
Naotaoshi Sugimoto,
Haruhiko Cho,
Yashushi Omuro,
Ken Kato,
M. Goto,
I. Hyodo,
Kazuhiro Yoshida,
H. Baba,
T. Esaki,
J. Furuse,
Wan Zamaniah Wan Mohammed,
Carlos Hernandez Hernandez,
Juan Casas Garcia,
Adriana Dominguez Andrade,
Katriona Clarke,
G. Hjortland,
N. Glenjen,
T. Kubiatowski,
J. Jacek,
M. Wojtukiewicz,
S. Lazarev,
Yuri Lancukhay,
Sergey Afanasayev,
V. Moiseyenko,
V. Kostorov,
S. Protsenko,
V. Shirinkin,
D. Sakaeva,
N. Fadeeva,
W. Yong,
C. Ng,
B. Robertson,
B. Rapaport,
G. Cohen,
L. Dreosti,
P. Ruff,
C. Jacobs,
G. Landers,
W. Szpak,
S. Roh,
Jeeyun Lee,
Yeul-Hong Kim,
H. Chung,
Maria Alsina Maqueda,
F. Longo MuΓ±oz,
Andres Cervantes Aguilar,
Enrique Aranda Aguilar,
P. GarcΓa Alfonso,
F. Rivera,
Jaime Feliu Batle,
R. Pazo Cid,
K. Yeh,
JenβShi Chen,
Y. Chao,
C. Yen,
O. Kara,
Ε. YalΓ§Δ±n,
D. Hochhauser,
I. Chau,
A. Benson,
V. Shankaran,
W. Shaib,
P. Philip,
V. Sharma,
R. Siegel,
Weijing Sun,
Z. Wainberg,
B. George,
A. Bullock,
S. Myrick,
Josephine Faruol,
Richard Siegel,
T. Larson,
C. Becerra,
Suresh Ratnam,
D. Richards,
Stephen L. Riche
|
9 |
2018 |
9
π
|
|
π
|
Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA
159 auth.
Min Liu,
G. Oxnard,
E. Klein,
C. Swanton,
C. Swanton,
M. Seiden,
Minetta C. Liu,
G. Oxnard,
E. Klein,
David Smith,
D. Richards,
Timothy J. Yeatman,
A. Cohn,
R. Lapham,
J. Clement,
...
A. Parker,
M. Tummala,
K. McIntyre,
M. Sekeres,
A. Bryce,
Robert W. Siegel,
Xuezhong Wang,
David P. Cosgrove,
N. Abu-Rustum,
J. Trent,
D. Thiel,
C. Becerra,
Manish Agrawal,
L. Garbo,
J. Giguere,
Ross M. Michels,
Ronald P. Harris,
S. Richey,
T. McCarthy,
D. Waterhouse,
F. Couch,
S. Wilks,
A. Krie,
R. Balaraman,
Alvaro Restrepo,
M. Meshad,
K. Rieger-Christ,
T. Sullivan,
Christine M. Lee,
D. R. Greenwald,
William Oh,
C. Tsao,
N. Fleshner,
H. Kennecke,
M. Khalil,
D. Spigel,
Atisha Manhas,
B. Ulrich,
P. Kovoor,
C. Stokoe,
Jay Courtright,
H. Yimer,
Timothy G. Larson,
C. Swanton,
C. Swanton,
M. Seiden,
S. Cummings,
Farnaz Absalan,
G. Alexander,
B. Allen,
Hamed Amini,
Alex Aravanis,
Siddhartha Bagaria,
L. Bazargan,
J. Beausang,
Jennifer R. Berman,
Craig M. Betts,
A. Blocker,
J. Bredno,
Calef Robert Abe Paine,
G. Cann,
J. Carter,
Christopher Chang,
H. Chawla,
Xiaoji Chen,
Tom C. Chien,
D. Civello,
Konstantin Davydov,
V. Demas,
Mohini Desai,
Zhao Dong,
Saniya Fayzullina,
Alexander P. Fields,
D. Filippova,
Peter Freese,
E. Fung,
S. Gnerre,
S. Gross,
M. Halks-Miller,
M. Hall,
A. Hartman,
C. Hou,
E. Hubbell,
N. Hunkapiller,
K. Jagadeesh,
A. Jamshidi,
R. Jiang,
B. Jung,
Taehyung Kim,
R. Klausner,
K. Kurtzman,
M. Lee,
Wendy-Ling Lin,
J. Lipson,
Hai Liu,
Qinwen Liu,
M. Lopatin,
T. Maddala,
M. C. Maher,
Collin Melton,
Andrea Mich,
S. Nautiyal,
Jonathan Newman,
Joshua Newman,
Nicula Virgil,
Cosmos Nicolaou,
Ongjen Nikolic,
Wenying Pan,
Shilpen A. Patel,
Sarah A Prins,
R. Rava,
Neda Ronaghi,
O. Sakarya,
R. Satya,
Jan Schellenberger,
Eric Scott,
A. Sehnert,
R. Shaknovich,
A. Shanmugam,
K. Shashidhar,
Ling Shen,
A. Shenoy,
S. Shojaee,
P. Singh,
Kristan K. Steffen,
Susan Tang,
J. Toung,
Anton Valouev,
Oliver Venn,
R. Williams,
Tony Wu,
Hui-Hong Xu,
Christopher Yakym,
X. Yang,
J. Yecies,
Alexander S. Yip,
J. Youngren,
J. Yue,
Jingyang Zhang,
Lily Zhang,
Lori Zhang,
N. Zhang,
C. Curtis,
D. Berry
|
9 |
2020 |
9
π
|
|
π
|
An exosome-based transcriptomic signature for noninvasive, early detection of patients with pancreatic ductal adenocarcinoma: A multicenter cohort study.
28 auth.
Kota Nakamura,
Zhongxu Zhu,
Souvick Roy,
E. Jun,
Haiyong Han,
R. MuΓ±oz,
S. Nishiwada,
G. Sharma,
D. Cridebring,
F. Zenhausern,
Seungchan Kim,
Denise J. Roe,
S. Darabi,
I. Han,
Douglas B. Evans,
...
S. Yamada,
M. Demeure,
C. Becerra,
Scott A. Celinski,
E. Borazanci,
S. Tsai,
Y. Kodera,
Joon-Oh Park,
John Bolton,
Xin Wang,
Song-Cheol Kim,
Daniel Von Hoff,
A. Goel
|
6 |
2022 |
6
π
|
|
π
|
Gemcitabine plus enzastaurin or single-agent gemcitabine in locally advanced or metastatic pancreatic cancer: Results of a Phase II, randomized, noncomparative study
15 auth.
D. Richards,
P. Kuefler,
C. Becerra,
L. Wilfong,
R. Gersh,
K. Boehm,
F. Zhan,
L. Asmar,
S. Myrand,
R. Hozak,
...
Luping Zhao,
J. Gill,
B. Mullaney,
C. Obasaju,
S. Nicol
|
5 |
2011 |
5
π
|
|
π
|
A phase Ib trial of IPI-926, a hedgehog pathway inhibitor, plus gemcitabine in patients with metastatic pancreatic cancer.
10 auth.
D. Richards,
J. Stephenson,
B. Wolpin,
C. Becerra,
J. Hamm,
W. Messersmith,
...
S. Devens,
J. Cushing,
T. Schmalbach,
C. Fuchs
|
5 |
2012 |
5
π
|
|
π
|
Phase I Study of CHK1 Inhibitor LY2603618 in Combination with Gemcitabine in Patients with Solid Tumors
14 auth.
E. Calvo,
F. Braiteh,
D. V. Von Hoff,
R. McWilliams,
C. Becerra,
M. Galsky,
G. Jameson,
Ji Lin,
S. McKane,
E. Wickremsinhe,
...
S. Hynes,
Aimee Bence Lin,
K. Hurt,
D. Richards
|
5 |
2016 |
5
π
|
|
π
|
The safety of IPI-926, a novel hedgehog pathway inhibitor, in combination with gemcitabine in patients (pts) with metastatic pancreatic cancer.
11 auth.
Joe Stephenson,
Donald A. Richards,
B. Wolpin,
C. Becerra,
J. T. Hamm,
W. Messersmith,
...
S. Devens,
J. Cushing,
J. Goddard,
T. Schmalbach,
Charles S. Fuchs
|
4 |
2011 |
4
π
|
|
π
|
A phase 1 clinical trial of ASG-5ME, a novel drug-antibody conjugate targeting SLC44A4, in patients with advanced pancreatic and gastric cancers
8 auth.
A. Coveler,
A. Ko,
D. Catenacci,
D. Hoff,
C. Becerra,
N. Whiting,
...
Jing Yang,
B. Wolpin
|
4 |
2016 |
4
π
|
|
π
|
A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer
20 auth.
A. Adjei,
D. Richards,
A. El-Khoueiry,
F. Braiteh,
C. Becerra,
J. Stephenson,
A. Hezel,
M. Sherman,
L. Garbo,
D. P. Leffingwell,
...
C. Iverson,
J. Miner,
Z. Shen,
L. Yeh,
Sonny Gunawan,
David M. Wilson,
Kimberly Manhard,
P. Rajagopalan,
H. Krissel,
N. Clendeninn
|
4 |
2015 |
4
π
|
|
π
|
A Phase Ib multicenter, dose-escalation study of the polyamine analogue PG-11047 in combination with gemcitabine, docetaxel, bevacizumab, erlotinib, cisplatin, 5-fluorouracil, or sunitinib in patients with advanced solid tumors or lymphoma
15 auth.
T. Murray Stewart,
D. V. Von Hoff,
Michael L. Fitzgerald,
L. Marton,
C. Becerra,
T. Boyd,
P. Conkling,
L. Garbo,
R. Jotte,
D. Richards,
...
David A. Smith,
J. Stephenson,
N. Vogelzang,
Hillary H. Wu,
R. Casero
|
3 |
2020 |
3
π
|
|
π
|
Abemaciclib in Combination With Endocrine Therapy for Patients With Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: A Phase 1b Study
19 auth.
S. Tolaney,
M. Beeram,
J. Beck,
A. Conlin,
E. Dees,
S. Puhalla,
B. Rexer,
H. Burris,
K. Jhaveri,
T. Helsten,
...
C. Becerra,
K. Kalinsky,
K. Moore,
Allison M. Manuel,
A. Lithio,
G. Price,
Sonya C. Chapman,
L. Litchfield,
M. Goetz
|
3 |
2022 |
3
π
|
