|
🐬
|
Reconstitution of γ-secretase activity
D. Edbauer,
E. Winkler,
J. Regula,
B. Pesold,
H. Steiner,
C. Haass
|
9 |
2003 |
9
🐬
|
|
🐬
|
A γ‐secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish
Andrea Geling,
H. Steiner,
M. Willem,
L. Bally-Cuif,
C. Haass
|
9 |
2002 |
9
🐬
|
|
🐜
|
Presenilin‐dependent γ‐secretase processing of β‐amyloid precursor protein at a site corresponding to the S3 cleavage of Notch
8 auth.
M. Sastre,
H. Steiner,
K. Fuchs,
A. Capell,
G. Multhaup,
M. Condron,
...
D. Teplow,
C. Haass
|
8 |
2001 |
8
🐜
|
|
🐬
|
Reconstitution of gamma-secretase activity.
D. Edbauer,
E. Winkler,
J. Regula,
B. Pesold,
H. Steiner,
C. Haass
|
8 |
2003 |
8
🐬
|
|
🦁
|
A Loss of Function Mutation of Presenilin-2 Interferes with Amyloid β-Peptide Production and Notch Signaling*
19 auth.
H. Steiner,
K. Duff,
A. Capell,
H. Romig,
M. G. Grim,
S. Lincoln,
J. Hardy,
X. Yu,
M. Picciano,
K. Fechteler,
...
M. Citron,
Raphael Kopan,
B. Pesold,
S. Keck,
M. Baader,
T. Tomita,
T. Iwatsubo,
R. Baumeister,
C. Haass
|
8 |
1999 |
8
🦁
|
|
🐜
|
Intracellular Generation and Accumulation of Amyloid β-Peptide Terminating at Amino Acid 42*
7 auth.
C. Wild‐Bode,
T. Yamazaki,
A. Capell,
U. Leimer,
H. Steiner,
Y. Ihara,
...
C. Haass
|
8 |
1997 |
8
🐜
|
|
🐢
|
Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Aβ42 production
11 auth.
Tobias Moehlmann,
E. Winkler,
Xuefeng Xia,
D. Edbauer,
J. Murrell,
A. Capell,
...
C. Kaether,
Hui Zheng,
B. Ghetti,
C. Haass,
H. Steiner
|
8 |
2002 |
8
🐢
|
|
🐜
|
Presenilin-dependent Intramembrane Proteolysis of CD44 Leads to the Liberation of Its Intracellular Domain and the Secretion of an Aβ-like Peptide*
10 auth.
S. Lammich,
M. Okochi,
M. Takeda,
C. Kaether,
A. Capell,
A. Zimmer,
...
D. Edbauer,
J. Walter,
H. Steiner,
C. Haass
|
8 |
2002 |
8
🐜
|
|
🦁
|
PEN-2 Is an Integral Component of the γ-Secretase Complex Required for Coordinated Expression of Presenilin and Nicastrin*
8 auth.
H. Steiner,
E. Winkler,
D. Edbauer,
S. Prokop,
Gabriele Basset,
Aya Yamasaki,
...
Marcus Kostka,
C. Haass
|
8 |
2002 |
8
🦁
|
|
🦁
|
Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases
12 auth.
H. Steiner,
Marcus Kostka,
H. Romig,
Gabriele Basset,
B. Pesold,
J. Hardy,
...
A. Capell,
L. Meyn,
M. Grim,
R. Baumeister,
K. Fechteler,
C. Haass
|
8 |
2000 |
8
🦁
|
|
🐢
|
Presenilin and nicastrin regulate each other and determine amyloid β-peptide production via complex formation
D. Edbauer,
E. Winkler,
C. Haass,
H. Steiner
|
7 |
2002 |
7
🐢
|
|
🐢
|
Regulated intramembrane proteolysis – lessons from amyloid precursor protein processing
S. Lichtenthaler,
C. Haass,
H. Steiner
|
7 |
2011 |
7
🐢
|
