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From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases
E. Cano-Gamez,
G. Trynka
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8 |
2020 |
8 🦁
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Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines
15 auth.
E. Cano-Gamez,
B. Soskic,
T. Roumeliotis,
E. So,
D. Smyth,
M. Baldrighi,
D. Willé,
N. Nakić,
J. Esparza-Gordillo,
C. Larminie,
...
P. Bronson,
D. Tough,
W. Rowan,
J. Choudhary,
G. Trynka
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7 |
2019 |
7 🦁
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🐜
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Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis
32 auth.
A. Kwok,
A. Allcock,
R. Ferreira,
E. Cano-Gamez,
M. Smee,
K. Burnham,
Y. Zurke,
A. Novak,
M. Darwent,
Tanya Baron,
Charlotte Brown,
S. Beer,
Alexis Espinosa,
Tine Panduro,
Dominique Georgiou,
...
J. Martinez,
H. Thraves,
Elena Perez,
Rocio Fernandez,
Alberto Sobrino,
Veronica Sanchez,
Rufino Magallano,
Kathryn P. Dineen,
Jean Wilson,
S. McKechnie,
A. Mentzer,
C. Monaco,
I. Udalova,
Charles Hinds,
J. Todd,
E. Davenport,
Julian C. Knight
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6 |
2023 |
6 🐜
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🐜
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Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases
12 auth.
B. Soskic,
E. Cano-Gamez,
D. Smyth,
W. Rowan,
N. Nakić,
J. Esparza-Gordillo,
...
L. Bossini‐Castillo,
D. Tough,
C. Larminie,
P. Bronson,
D. Willé,
G. Trynka
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6 |
2019 |
6 🐜
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Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation
17 auth.
B. Soskic,
E. Cano-Gamez,
D. Smyth,
K. Ambridge,
Ziying Ke,
J. Matte,
L. Bossini‐Castillo,
J. Kaplanis,
Lucia Ramirez-Navarro,
A. Lorenc,
...
N. Nakić,
J. Esparza-Gordillo,
W. Rowan,
D. Willé,
D. Tough,
P. Bronson,
G. Trynka
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6 |
2021 |
6 🐜
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Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney
33 auth.
Xiao Jiang,
James M. Eales,
David Scannali,
Alicja Nazgiewicz,
P. Prestes,
M. Maier,
M. Denniff,
Xiaoguang Xu,
Sushant Saluja,
E. Cano-Gamez,
W. Wystrychowski,
M. Szulińska,
A. Antczak,
S. Byars,
D. Skrypnik,
...
M. Głyda,
R. Król,
J. Żywiec,
E. Zukowska-szczechowska,
L. Burrell,
A. Woolf,
A. Greenstein,
P. Bogdański,
B. Keavney,
A. Morris,
A. Heagerty,
B. Williams,
S. Harrap,
G. Trynka,
N. Samani,
T. Guzik,
F. Charchar,
M. Tomaszewski
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5 |
2020 |
5 🐜
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An immune dysfunction score for stratification of patients with acute infection based on whole blood gene expression
17 auth.
E. Cano-Gamez,
K. Burnham,
Cyndi Goh,
A. Allcock,
Zunaira H. Malick,
Lauren Overend,
A. Kwok,
D. A. Smith,
H. Peters-Sengers,
D. Antcliffe,
...
S. McKechnie,
B. Scicluna,
T. van der Poll,
A. Gordon,
Charles Hinds,
E. Davenport,
J. Knight
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5 |
2022 |
5 🦁
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Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney
49 auth.
James M. Eales,
Xiao Jiang,
Xiaoguang Xu,
Sushant Saluja,
A. Akbarov,
E. Cano-Gamez,
M. McNulty,
C. Finan,
Hui Guo,
W. Wystrychowski,
M. Szulińska,
Huw B. Thomas,
Sanjeev Pramanik,
S. Chopade,
P. Prestes,
...
I. Wise,
E. Evangelou,
M. Salehi,
Yusif Shakanti,
M. Ekholm,
M. Denniff,
Alicja Nazgiewicz,
Felix Eichinger,
B. Godfrey,
A. Antczak,
M. Głyda,
R. Król,
S. Eyre,
Jason J. Brown,
C. Berzuini,
J. Bowes,
M. Caulfield,
E. Zukowska-szczechowska,
J. Żywiec,
P. Bogdański,
M. Kretzler,
A. Woolf,
David Talavera,
B. Keavney,
P. Maffia,
T. Guzik,
R. O’Keefe,
G. Trynka,
N. Samani,
A. Hingorani,
M. Sampson,
A. Morris,
F. Charchar,
M. Tomaszewski
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5 |
2021 |
5 🐜
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Immune disease variants modulate gene expression in regulatory CD4+ T cells
17 auth.
L. Bossini‐Castillo,
Dafni A. Glinos,
Natalia Kunowska,
Gosia Golda,
A. Lamikanra,
M. Spitzer,
B. Soskic,
E. Cano-Gamez,
D. Smyth,
Claire Cattermole,
...
Kaur Alasoo,
Alice L. Mann,
Kousik Kundu,
N. Soranzo,
I. Dunham,
David J. Roberts,
G. Trynka
|
5 |
2019 |
5 🐜
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