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🐜
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Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
12 auth.
A. Calignon,
M. Polydoro,
Marc Suárez-Calvet,
Christopher M. William,
David H. Adamowicz,
Katherine J. Kopeikina,
...
Rose Pitstick,
N. Sahara,
K. Ashe,
G. Carlson,
T. Spires-Jones,
B. Hyman
|
10 |
2012 |
10
🐜
|
|
🦁
|
The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease
T. Spires-Jones,
B. Hyman
|
9 |
2014 |
9
🦁
|
|
🐜
|
Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease
10 auth.
Melanie Meyer-Luehmann,
T. Spires-Jones,
C. Prada,
M. Garcia-Alloza,
A. Calignon,
Anete Rozkalne,
...
J. Koenigsknecht-Talboo,
D. Holtzman,
B. Bacskai,
B. Hyman
|
9 |
2008 |
9
🐜
|
|
🐢
|
Oligomeric amyloid β associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
12 auth.
Robert M. Koffie,
Melanie Meyer-Luehmann,
T. Hashimoto,
Kenneth W Adams,
Matthew L Mielke,
M. Garcia-Alloza,
...
Kristina D. Micheva,
Stephen J. Smith,
M. L. Kim,
V. Lee,
B. Hyman,
T. Spires-Jones
|
9 |
2009 |
9
🐢
|
|
🐜
|
Caspase activation precedes and leads to tangles
7 auth.
A. Calignon,
L. Fox,
Rose Pitstick,
G. Carlson,
B. Bacskai,
T. Spires-Jones,
...
B. Hyman
|
9 |
2010 |
9
🐜
|
|
🐬
|
The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system.
Hwan‐Ching Tai,
A. Serrano‐Pozo,
T. Hashimoto,
M. Frosch,
T. Spires-Jones,
B. Hyman
|
8 |
2012 |
8
🐬
|
|
🐜
|
Amyloid β Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation
12 auth.
Hai‐yan Wu,
E. Hudry,
T. Hashimoto,
K. Kuchibhotla,
Anete Rozkalne,
Z. Fan,
...
T. Spires-Jones,
Hong Xie,
Michal Arbel-Ornath,
C. Grosskreutz,
B. Bacskai,
B. Hyman
|
8 |
2010 |
8
🐜
|
|
🐜
|
Tau association with synaptic vesicles causes presynaptic dysfunction
17 auth.
Lujia Zhou,
Joseph McInnes,
Keimpe D. Wierda,
M. Holt,
A. Herrmann,
Rosemary J. Jackson,
Yu-Chun Wang,
J. Swerts,
J. Beyens,
K. Miśkiewicz,
...
Sven Vilain,
I. Dewachter,
D. Moechars,
B. de Strooper,
T. Spires-Jones,
Joris de Wit,
P. Verstreken
|
8 |
2017 |
8
🐜
|
|
🦁
|
Interactions of pathological proteins in neurodegenerative diseases
T. Spires-Jones,
J. Attems,
D. Thal
|
8 |
2017 |
8
🦁
|
|
🦁
|
Tau pathophysiology in neurodegeneration: a tangled issue
T. Spires-Jones,
William H. Stoothoff,
A. Calignon,
P. Jones,
B. Hyman
|
8 |
2009 |
8
🦁
|
|
🐢
|
Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β.
13 auth.
Robert M. Koffie,
T. Hashimoto,
Hwan‐Ching Tai,
Kevin R. Kay,
A. Serrano‐Pozo,
Daniel Joyner,
Steven S. Hou,
Katherine J. Kopeikina,
M. Frosch,
V. Lee,
...
D. Holtzman,
B. Hyman,
T. Spires-Jones
|
8 |
2012 |
8
🐢
|
|
🐜
|
Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers II: Sigma-2/PGRMC1 Receptors Mediate Abeta 42 Oligomer Binding and Synaptotoxicity
21 auth.
N. Izzo,
Jinbin Xu,
C. Zeng,
Molly J. Kirk,
Kelsie Mozzoni,
Colleen Silky,
Courtney Rehak,
Raymond Yurko,
G. Look,
G. Rishton,
...
Hank Safferstein,
C. Cruchaga,
A. Goate,
M. Cahill,
O. Arancio,
R. Mach,
R. Craven,
E. Head,
H. Levine,
T. Spires-Jones,
Susan M. Catalano
|
8 |
2014 |
8
🐜
|
