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🐜
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Phosphatidylinositol‐3,4,5‐trisphosphate (PtdIns‐3,4,5‐P3)/Tec kinase‐dependent calcium signaling pathway: a target for SHIP‐mediated inhibitory signals
10 auth.
A. Scharenberg,
O. El‐Hillal,
D. Fruman,
L. Beitz,
Zuomei Li,
Siqi Lin,
...
I. Gout,
L. Cantley,
D. Rawlings,
J. Kinet
|
8 |
1998 |
8
🐜
|
|
🐜
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Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B‐cell receptor activation
10 auth.
A. Fluckiger,
Zuomei Li,
R. Kato,
M. Wahl,
H. Ochs,
R. Longnecker,
...
J. Kinet,
O. Witte,
A. Scharenberg,
D. Rawlings
|
8 |
1998 |
8
🐜
|
|
🐢
|
MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo
20 auth.
M. Fournel,
C. Bonfils,
Yunyan Hou,
P. T. Yan,
Marie-Claude Trachy-Bourget,
A. Kalita,
Jianhong Liu,
Ai-hua Lu,
Nancy Z. Zhou,
M. Robert,
...
Jeff Gillespie,
James Wang,
H. Ste-Croix,
J. Rahil,
S. Lefèbvre,
O. Moradei,
D. Delorme,
A. Macleod,
J. Besterman,
Zuomei Li
|
8 |
2008 |
8
🐢
|
|
🐜
|
Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia.
19 auth.
G. Garcia-Manero,
S. Assouline,
J. Cortes,
Z. Estrov,
H. Kantarjian,
Hui Yang,
W. Newsome,
W. Miller,
C. Rousseau,
A. Kalita,
...
C. Bonfils,
M. Dubay,
Tracy Patterson,
Zuomei Li,
J. Besterman,
G. Reid,
E. Laille,
R. Martell,
M. Minden
|
7 |
2008 |
7
🐜
|
|
🦁
|
Phosphatidylinositol 3-kinase-γ activates Bruton’s tyrosine kinase in concert with Src family kinases
Zuomei Li,
M. Wahl,
A. Eguinoa,
L. Stephens,
P. Hawkins,
O. Witte
|
7 |
1997 |
7
🦁
|
|
🐜
|
Mocetinostat for relapsed classical Hodgkin's lymphoma: an open-label, single-arm, phase 2 trial.
18 auth.
A. Younes,
Y. Oki,
Gregory Bociek,
J. Kuruvilla,
M. Fanale,
S. Neelapu,
A. Copeland,
D. Buglio,
A. Galal,
Jeff rey Besterman,
...
Zuomei Li,
M. Drouin,
Tracy Patterson,
Renee Ward,
Jessica K. Paulus,
Yuan Ji,
Jeff rey Medeiros,
Robert E. Martell
|
7 |
2011 |
7
🐜
|
|
🐜
|
Novel aminophenyl benzamide-type histone deacetylase inhibitors with enhanced potency and selectivity.
18 auth.
O. Moradei,
Tammy C. Mallais,
Sylvie Fréchette,
I. Paquin,
Pierre E Tessier,
S. Leit,
M. Fournel,
C. Bonfils,
Marie-Claude Trachy-Bourget,
Jianhong Liu,
...
T. Yan,
Ai-hua Lu,
J. Rahil,
James Wang,
S. Lefèbvre,
Zuomei Li,
A. Vaisburg,
J. Besterman
|
7 |
2007 |
7
🐜
|
|
🐜
|
Phase I study of MGCD0103 given as a three-times-per-week oral dose in patients with advanced solid tumors.
16 auth.
L. Siu,
R. Pili,
I. Durán,
W. Messersmith,
E. Chen,
R. Sullivan,
M. Maclean,
Serina King,
S. Brown,
G. Reid,
...
Zuomei Li,
A. Kalita,
E. Laille,
J. Besterman,
R. Martell,
M. Carducci
|
6 |
2008 |
6
🐜
|
|
🐜
|
Discovery of N-(2-aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide (MGCD0103), an orally active histone deacetylase inhibitor.
23 auth.
Nancy Z. Zhou,
O. Moradei,
S. Raeppel,
S. Leit,
Sylvie Fréchette,
F. Gaudette,
I. Paquin,
Naomy Bernstein,
Giliane Bouchain,
A. Vaisburg,
...
Zhiyun Jin,
Jeff Gillespie,
James Wang,
M. Fournel,
P. T. Yan,
Marie-Claude Trachy-Bourget,
A. Kalita,
Ai-hua Lu,
J. Rahil,
A. Macleod,
Zuomei Li,
J. Besterman,
D. Delorme
|
6 |
2008 |
6
🐜
|
|
🐢
|
Sulfonamide anilides, a novel class of histone deacetylase inhibitors, are antiproliferative against human tumors.
14 auth.
M. Fournel,
Marie-Claude Trachy-Bourget,
P. T. Yan,
A. Kalita,
C. Bonfils,
Carole Beaulieu,
Sylvie Fréchette,
S. Leit,
E. Abou-Khalil,
S. Woo,
...
D. Delorme,
A. Macleod,
J. Besterman,
Zuomei Li
|
6 |
2002 |
6
🐢
|
|
🐬
|
Val-->Ala mutations selectively alter helix-helix packing in the transmembrane segment of phage M13 coat protein.
C. Deber,
Amir R. Khan,
Zuomei Li,
C. Joensson,
M. Glibowicka,
Jing Wang
|
6 |
1993 |
6
🐬
|
