|
π
|
R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling
32 auth.
R. Su,
Lei Dong,
Chenying Li,
S. Nachtergaele,
M. Wunderlich,
Y. Qing,
Xiaolan Deng,
Yungui Wang,
X. Weng,
Chao Hu,
Meng-xia Yu,
Jennifer Skibbe,
Qinglong Dai,
D. Zou,
Tong Wu,
...
Kangkang Yu,
Hengyou Weng,
Huilin Huang,
Kyle Ferchen,
Xi Qin,
Bin Zhang,
J. Qi,
A. Sasaki,
D. Plas,
J. Bradner,
Minjie Wei,
G. Marcucci,
Xi Jiang,
J. Mulloy,
Jie Jin,
Chuan He,
Jianjun Chen
|
9 |
2018 |
9
π
|
|
π
|
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification.
29 auth.
Hengyou Weng,
Huilin Huang,
Huizhe Wu,
Xi Qin,
B. Zhao,
Lei Dong,
Hailing Shi,
Jennifer Skibbe,
Chao Shen,
Chao Hu,
Yue Sheng,
Yungui Wang,
M. Wunderlich,
Bin Zhang,
Louis C. DorΓ©,
...
R. Su,
Xiaolan Deng,
Kyle Ferchen,
Chenying Li,
Miao Sun,
Zhike Lu,
Xi Jiang,
G. Marcucci,
J. Mulloy,
Jianhua Yang,
Zhijian Qian,
M. Wei,
Chuan He,
Jianjun Chen
|
9 |
2017 |
9
π
|
|
π
|
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion.
39 auth.
R. Su,
Lei Dong,
Yangchan Li,
Min Gao,
Li Han,
M. Wunderlich,
Xiaolan Deng,
Hongzhi Li,
Yue Huang,
Lei Gao,
Chenying Li,
Zhicong Zhao,
S. Robinson,
B. Tan,
Y. Qing,
...
Xi Qin,
Emily A. Prince,
Jun Xie,
H. Qin,
Wei Li,
Chao Shen,
Jie Sun,
Prakash Kulkarni,
Hengyou Weng,
Huilin Huang,
Zhenhua Chen,
Bin Zhang,
Xiwei Wu,
M. Olsen,
M. MΓΌschen,
G. Marcucci,
R. Salgia,
Ling Li,
A. Fathi,
Zejuan Li,
J. Mulloy,
M. Wei,
D. Horne,
Jianjun Chen
|
9 |
2020 |
9
π
|
|
π¦
|
Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia.
10 auth.
Bin Zhang,
Yinwei Ho,
Qin Huang,
Takahiro Maeda,
A. Lin,
Sung-Uk Lee,
...
A. Hair,
T. Holyoake,
C. Huettner,
R. Bhatia
|
8 |
2012 |
8
π¦
|
|
π¦
|
Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.
11 auth.
Bin Zhang,
A. Strauss,
S. Chu,
Min Li,
Yinwei Ho,
K. Shiang,
...
D. Snyder,
C. Huettner,
L. Shultz,
T. Holyoake,
R. Bhatia
|
8 |
2010 |
8
π¦
|
|
π¦
|
Microenvironmental protection of CML stem and progenitor cells from tyrosine kinase inhibitors through N-cadherin and Wnt-Ξ²-catenin signaling.
8 auth.
Bin Zhang,
Min Li,
Tinisha McDonald,
T. Holyoake,
R. Moon,
D. Campana,
...
L. Shultz,
R. Bhatia
|
8 |
2012 |
8
π¦
|
|
π
|
RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia.
24 auth.
Chao Shen,
Yue Sheng,
Allen C. Zhu,
S. Robinson,
Xi Jiang,
Lei Dong,
Huiying Chen,
R. Su,
Zhe Yin,
Wei Li,
...
Xiaolan Deng,
Yinhuai Chen,
Yueh-Chiang Hu,
Hengyou Weng,
Huilin Huang,
Emily A. Prince,
C. Cogle,
Miao Sun,
Bin Zhang,
Chun-Wei Chen,
G. Marcucci,
Chuan He,
Zhijian Qian,
Jianjun Chen
|
8 |
2020 |
8
π
|
|
π
|
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival.
12 auth.
A. Hamilton,
V. Helgason,
M. Schemionek,
Bin Zhang,
S. Myssina,
E. Allan,
...
F. Nicolini,
C. MΓΌller-Tidow,
R. Bhatia,
V. Brunton,
S. Koschmieder,
T. Holyoake
|
7 |
2012 |
7
π
|
|
π
|
The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1.
7 auth.
C. Popovici,
Bin Zhang,
M. GrΓ©goire,
P. Jonveaux,
M. Lafage-Pochitaloff,
D. Birnbaum,
...
M. PΓ©busque
|
7 |
1999 |
7
π
|
|
π
|
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival
12 auth.
A. Hamilton,
G. Helgason,
M. Schemionek,
Bin Zhang,
S. Myssina,
E. Allan,
...
F. Nicolini,
C. MΓΌller-Tidow,
R. Bhatia,
V. Brunton,
S. Koschmieder,
T. Holyoake
|
7 |
2012 |
7
π
|
|
π
|
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis.
29 auth.
Y. Qing,
Lei Dong,
Lei Gao,
Chenying Li,
Yangchan Li,
Li Han,
Emily A. Prince,
B. Tan,
Xiaolan Deng,
Collin Wetzel,
Chao Shen,
Min Gao,
Zhenhua Chen,
Wei Li,
Bin Zhang,
...
D. Braas,
J. ten Hoeve,
G. Sanchez,
Huiying Chen,
L. Chan,
Chun-Wei Chen,
D. Ann,
Lei Jiang,
M. MΓΌschen,
G. Marcucci,
D. Plas,
Zejuan Li,
R. Su,
Jianjun Chen
|
7 |
2021 |
7
π
|
|
π
|
Combined targeting of BCL-2 and BCR-ABL tyrosine kinase eradicates chronic myeloid leukemia stem cells
14 auth.
B. Carter,
P. Mak,
H. Mu,
Hong-sheng Zhou,
D. Mak,
W. Schober,
J. Leverson,
Bin Zhang,
R. Bhatia,
Xuelin Huang,
...
J. Cortes,
H. Kantarjian,
M. Konopleva,
M. Andreeff
|
7 |
2016 |
7
π
|
