| Title | Claps | Level | Year | L/Y |
|---|---|---|---|---|
|
Genetic Variants in REC8, RNF212, and PRDM9 Influence Male Recombination in Cattle
C. Sandor, Wanbo Li, W. Coppieters, T. Druet, C. Charlier, M. Georges
We use >250,000 cross-over events identified in >10,000 bovine sperm cells to perform an extensive characterization of meiotic recombination in male cattle. We map Quantitative Trait Loci (QTL) influencing genome-wide recombination rate, genome-wide…
We use >250,000 cross-over events identified in >10,000 bovine sperm cells to perform an extensive characterization of meiotic recombination in male cattle. We map Quantitative Trait Loci (QTL) influencing genome-wide recombination rate, genome-wide hotspot usage, and locus-specific recombination rate. We fine-map three QTL and present strong evidence that genetic variants in REC8 and RNF212 influence genome-wide recombination rate, while genetic variants in PRDM9 influence genome-wide hotspot usage.
Published in
PLoS Genetics
|
4
|
7 | 2012 |
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