| Title | Claps | Level | Year | L/Y |
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Symptomatic primary intracranial neoplasms in Nigeria, West Africa
O. Idowu, E. Akang, A. Malomo
Objective: Intracranial tumours hitherto said to be rare in Africans is one of the most devastating forms of human cancers. There are many differences reported according to the geographic distribution, histological type, gender predisposition and an…
Objective: Intracranial tumours hitherto said to be rare in Africans is one of the most devastating forms of human cancers. There are many differences reported according to the geographic distribution, histological type, gender predisposition and anatomic location of these tumours. Our aim was to determine the frequency of histopathological variants of primary intracranial neoplasms, gender and age distribution, and intracranial location of symptomatic brain tumours in our environment. Method: The histological request forms and slides of 113 consecutive patients with symptomatic primary intracranial tumours necessitating surgical intervention (January 1999 to December 2004) were reviewed. Tumours were reclassified histologically according to the revised World Health Organisation (WHO) classification of tumours of the nervous system. Result: The tumours were more common in males with a gender ratio of 1.2: 1. Though these ratio was significantly reversed in the meningioma group (1:3.3). The common tumours are gliomas (23%), meningiomas (23%), pituitary adenoma (16.8%), craniopharyngiomas (15.9%), and medulloblastoma (12.4%). Medulloblastomas, gliomas and craniopharyngiomas accounted for over 85% of paediatric tumours. In paediatric age group, most of the tumours were malignant (69%) compared to adults (25.4%). In the adult population, over 80% of these tumours were meningiomas (35%), pituitary adenomas (27%) or gliomas (21.1%). Germ cell tumours were found to be uncommon. Conclusion: In adults and children the most common tumour is meningiomas and medulloblastoma respectively. Gliomas occur much less frequently compared to Caucasians. The low proportion of glioma could be related to facilities and manpower which delays or prevent diagnosis
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5 | 2007 |
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