| Title | Claps | Level | Year | L/Y |
|---|---|---|---|---|
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Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X
9 auth. R. Hagerman, M. Leehey, W. Heinrichs, F. Tassone, R. Wilson, J. Hills, ...
The authors report five elderly men with the fragile X premutation who had a progressive action tremor associated with executive function deficits and generalized brain atrophy. These individuals had elevated fragile X mental retardation 1 gene (FMR…
The authors report five elderly men with the fragile X premutation who had a progressive action tremor associated with executive function deficits and generalized brain atrophy. These individuals had elevated fragile X mental retardation 1 gene (FMR1) messenger RNA and normal or borderline levels of FMR1 protein. The authors propose that elevations of FMR1 messenger RNA may be causative for a neurodegenerative syndrome in a subgroup of elderly men with the FMR1 premutation.
Published in
Neurology
|
19
|
8 | 2001 |
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