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Viability and Outcomes With Revascularization or Medical Therapy in Ischemic Ventricular Dysfunction
24 auth. D. Perera, M. Ryan, H. Morgan, J. Greenwood, Mark C Petrie, M. Dodd, R. Weerackody, Peter O’Kane, P. Masci, M. Nazir, ... A. Papachristidis, N. Chahal, R. Khattar, Saad M. Ezad, S. Kapetanakis, Lana Dixon, Kalpa de Silva, A. Mcdiarmid, M. Marber, T. Mcdonagh, Gerry Mccann, Tim C. Clayton, Roxy Senior, A. Chiribiri
Key Points Question Does myocardial viability testing identify patients with ischemic left ventricular dysfunction who benefit from percutaneous coronary intervention? Findings In this prespecified subgroup analysis of a randomized clinical trial of…
Key Points Question Does myocardial viability testing identify patients with ischemic left ventricular dysfunction who benefit from percutaneous coronary intervention? Findings In this prespecified subgroup analysis of a randomized clinical trial of 610 participants with ischemic left ventricular dysfunction 35% or less, myocardial viability testing with cardiovascular magnetic resonance imaging or stress echocardiography did not identify a population of patients who benefit from percutaneous coronary intervention. The extent of nonviable myocardium was associated with a higher risk of death or hospitalization for heart failure and a lower chance of improvement in left ventricular function. Meaning Findings suggest that the extent of dysfunctional yet viable myocardium was not associated with revascularization outcomes.
Published in JAMA cardiology
1
5 2023