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Factors associated with suboptimal response to monoclonal antibodies in severe asthma
13 auth. L. A. Pérez de Llano, N. Marina Malanda, I. Urrutia, E. Martínez-Moragón, J. Gullón-Blanco, R. Díaz-Campos, M. Esquerre, Habernau Mena Alicia, B. Cosío, C. Cisneros, ...
ORCID Lara Dühring https://orcid.org/0000-0001-7978-4618 Jochen Behrends https://orcid.org/0000-0002-0648-8911 Theresa Walsemann https://orcid.org/0000-0001-5586-1885 Susann Dehmel https://orcid.org/0000-0003-4860-2767 Uta Jappe https://orcid.org/00…
ORCID Lara Dühring https://orcid.org/0000-0001-7978-4618 Jochen Behrends https://orcid.org/0000-0002-0648-8911 Theresa Walsemann https://orcid.org/0000-0001-5586-1885 Susann Dehmel https://orcid.org/0000-0003-4860-2767 Uta Jappe https://orcid.org/0000-0001-5602-3672 Johann Rahmöller https://orcid.org/0000-0002-5683-4181 Marc Ehlers https://orcid.org/0000-0002-5383-8603 R E FE R E N C E S 1. Gao P, Simpson JL, Zhang J, Gibson PG. Galectin3: its role in asthma and potential as an antiinflammatory target. Respir Res. 2013;14(1):136. doi:10.1186/1465992114136 PMID: 24313993. Review. 2. Shade KT, Platzer B, Washburn N, et al. Anthony RM.J a single glycan on IgE is indispensable for initiation of anaphylaxis. J Exp Med. 2015;212(4):457467. doi:10.1084/jem.20142182 PMID: 25824821. 3. Duan S, KoziolWhite CJ, Jester WF Jr, et al. CD33 recruitment inhibits IgEmediated anaphylaxis and desensitizes mast cells to allergen. J Clin Invest. 2019;129:13871401. doi:10.1172/JCI125456 PMID: 30645205. 4. Bartsch YC, Eschweiler S, Leliavski A, et al. IgG fc sialylation is regulated during the germinal center reaction upon immunization with different adjuvants. J Allergy Clin Immunol. 2020;146(3):652666. doi:10.1016/j.jaci.2020.04.059 PMID: 32445838. 5. Plomp R, Hensbergen PJ, Rombouts Y, et al. Sitespecific Nglycosylation analysis of human immunoglobulin E. J Proteome Res. 2014;13(2):536546. doi:10.1021/pr400714w PMID: 24308486. 6. Shade KC, Conroy ME, Washburn N, et al. Sialylation of immunoglobulin E is a determinant of allergic pathogenicity. Nature. 2020;582(7811):265270. doi:10.1038/s415860202311z PMID: 32499653. 7. Petry J, Rahmöller J, Dühring L, et al. Enriched blood IgG sialylation attenuates IgGmediated and IgGcontrolledIgEmediated allergic reactions. J Allergy Clin Immunol. 2021;147(2):763767. doi:10.1016/j.jaci.2020.05.056 PMID: 32603664.
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