| Title | Claps | Level | Year | L/Y |
|---|---|---|---|---|
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ALS susceptibility genes
Ighl Ights, Tim Harris
had an increase in H3K27ac or H3K4me2 levels in human tissues compared to rhesus macaque and mouse tissues. Using available corticogenesis expression data, they generated a network model of cortical development and identified 96 sets of genes with h…
had an increase in H3K27ac or H3K4me2 levels in human tissues compared to rhesus macaque and mouse tissues. Using available corticogenesis expression data, they generated a network model of cortical development and identified 96 sets of genes with highly correlated expression (modules). They integrated the lists of enhancers and promoters with human increases in H3K27ac or H3K4me2 signals and identified 17 modules that were enriched for these signals. These modules include genes associated with cortical development, neuronal progenitor proliferation, the extracellular matrix, and TGF-β and FGF signaling. EN
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0
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0 | 2015 |
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