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Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy
39 auth. F. Herrera, C. Ronet, M. Ochoa de Olza, D. Barras, I. Crespo, M. Andreatta, J. Corria-Osorio, A. Spill, F. Benedetti, R. Genolet, A. Orcurto, M. Imbimbo, Eleonora Ghisoni, B. Navarro Rodrigo, D. Berthold, ... A. Sarivalasis, K. Zaman, R. Duran, C. Dromain, John O. Prior, N. Schaefer, J. Bourhis, G. Dimopoulou, Z. Tsourti, Marius Messemaker, Thomas H Smith, S. Warren, P. Foukas, S. Rusakiewicz, M. Pittet, S. Zimmermann, C. Sempoux, U. Dafni, A. Harari, L. Kandalaft, Santiago J. Carmona, Denarda Dangaj Laniti, M. Irving, G. Coukos
Low-dose radiotherapy triggered T-cell infiltration into poorly inflamed tumors and reprogrammed both the adaptive and innate immune landscape to allow responsiveness to combinatorial immunotherapy.
Low-dose radiotherapy triggered T-cell infiltration into poorly inflamed tumors and reprogrammed both the adaptive and innate immune landscape to allow responsiveness to combinatorial immunotherapy.
Published in Cancer Discovery
1
7 2021