| Title | Claps | Level | Year | L/Y |
|---|---|---|---|---|
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Evaluation of treatment effects in patients with endometrial cancer and POLE mutations: An individual patient data meta‐analysis
23 auth. J. McAlpine, D. Chiu, R. Nout, D. Church, Pascal Schmidt, S. Lam, S. Leung, S. Bellone, Adele Wong, S. Brucker, ...
Endometrial cancers (ECs) with somatic mutations in DNA polymerase epsilon (POLE) are characterized by unfavorable pathological features, which prompt adjuvant treatment. Paradoxically, women with POLE‐mutated EC have outstanding clinical outcomes, …
Endometrial cancers (ECs) with somatic mutations in DNA polymerase epsilon (POLE) are characterized by unfavorable pathological features, which prompt adjuvant treatment. Paradoxically, women with POLE‐mutated EC have outstanding clinical outcomes, and this raises concerns of overtreatment. The authors investigated whether favorable outcomes were independent of treatment.
Published in
Cancer
|
9
|
6 | 2021 |
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