| Title | Claps | Level | Year | L/Y |
|---|---|---|---|---|
|
Increased intraplatelet levels of platelet‐derived growth factor and transforming growth factor‐β in patients with myelofibrosis with myeloid metaplasia
M. Martyré, H. Magdelenat, M. Bryckaert, C. Lainé-Bidron, F. Calvo
Summary. Platelet‐derived growth factor (PDGF) is thought to play some role in the genesis of fibrosis associated with myeloproliferative disorders. In addition, transforming growth factor‐β (TGF‐β) has been confirmed to promote fibrotic process. Bo…
Summary. Platelet‐derived growth factor (PDGF) is thought to play some role in the genesis of fibrosis associated with myeloproliferative disorders. In addition, transforming growth factor‐β (TGF‐β) has been confirmed to promote fibrotic process. Both PDGF and TGF‐β have been shown to cooperate with epidermal growth factor (EGF) in regulating the growth of human marrow fibroblasts. All three are contained in platelet α‐granules.
Published in
British Journal of Haematology
|
18
|
7 | 1991 |
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