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Title Claps Level Year L/Y
CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis
13 auth. Stéphane M Camus, Marine D. Camus, Carmen Figueras-Novoa, Gaelle Boncompain, L. A. Sadacca, Christopher Esk, A. Bigot, G. W. Gould, Dimitrios Kioumourtzoglou, F. Perez, ... Nia J. Bryant, Shaeri Mukherjee, Frances M. Brodsky
Blood glucose clearance relies on insulin-stimulated exocytosis of glucose transporter 4 (GLUT4) from sites of sequestration in muscle and fat. This work demonstrates that, in humans, CHC22 clathrin controls GLUT4 traffic from the ER-to-Golgi interm…
Blood glucose clearance relies on insulin-stimulated exocytosis of glucose transporter 4 (GLUT4) from sites of sequestration in muscle and fat. This work demonstrates that, in humans, CHC22 clathrin controls GLUT4 traffic from the ER-to-Golgi intermediate compartment to sites of sequestration during GLUT4 pathway biogenesis.
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4 2019