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Title Claps Level Year L/Y
Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architecture
12 auth. Thomas Eychenne, Elizaveta Novikova, M. Barrault, O. Alibert, Claire Boschiero, Nuno Peixeiro, ... David Cornu, V. Redeker, L. Kuras, P. Nicolas, M. Werner, J. Soutourina
Here, Eychenne et al. analyzed how Mediator acts in preinitiation complex (PIC) assembly using in vivo, in vitro, and in silico approaches, and their data suggest a key interaction between Mediator and TFIIB in this process. This study provides nove…
Here, Eychenne et al. analyzed how Mediator acts in preinitiation complex (PIC) assembly using in vivo, in vitro, and in silico approaches, and their data suggest a key interaction between Mediator and TFIIB in this process. This study provides novel mechanistic insights into the coordinated function of Mediator and TFIIB in PIC assembly in different chromatin contexts.
Published in Genes & Development
2
5 2016